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The Distribution of I/D Polymorphism in the ACE Gene betweenKorean Young Controls and Athletes

이재구 1 백두진 2 강병용 3 장민희 4 이강오 4

1삼육대학교
2한양대학교
3삼육대학교 생명과학연구소
4삼육대학교 생명과학과

Candidate

ABSTRACT

A number of genetic and environmental factors influence athletic performance. Cardiovascular fitness is an important factor of athletic success, and ACE gene is a good candidate for regulating cardiac and vascular function. Because younger subjects have less chance of being exposed to environmental factors than older ones, genetic factors have a relatively greater influence on younger subjects. The aim of this study was to investigate the distribution of I/D polymorphism in the ACE gene between Korean young controls and athletes. By association study, there were no significant differences in genotype and allele distributions between two groups, respectively (P¤0.05). When stratified by sporting disciplines, the significant difference in distribution was not also detected in our study (P¤0.05). These results do not support the hypothesis that the I/D polymorphism in the ACE gene is associated with endurance performance in Korean young subjects.

Citation status

* References for papers published after 2023 are currently being built.