@article{ART001143844},
author={이준혁 and Yung Hyun Choi and 최병태},
title={Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2004},
volume={17},
number={1},
pages={11-18},
doi={10.11637/aba.2004.17.1.11}
TY - JOUR
AU - 이준혁
AU - Yung Hyun Choi
AU - 최병태
TI - Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat
JO - Anatomy & Biological Anthropology
PY - 2004
VL - 17
IS - 1
PB - 대한체질인류학회
SP - 11
EP - 18
SN - 2671-5651
AB - We investigated the comparative effects of electroacupuncture (EA) with different frequency on the spinal c-fos and
inotropic glutamate receptor expression in carrageenan-injected rats. Bilateral EA stimulation with 2, 15 and 120 Hz
were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles. The inhibitory effects
of the EA on the inflammatory process were investigated in the central nociceptive sites by immunohistochemical analysis.
Three hours after carrageenan injection, the number of c-fos-like immunoreactive (LI) neurons was significantly
increased in all layers of the ipsilateral spinal cord at L4-5 segment. But these immunoreactive neurons were markedly
reduced in the spinal gray matter, especially in the superficial laminae, by all kinds of EA stimulation. The number of
NMDA(NR-1 and NR-2A) and AMPA receptors (GluR-1, GluR-2/3)-LI neurons was also increased by carrageenan
injection. But NR-2A-LI neuron was significantly reduced in superficial laminae of dorsal horn by 2 Hz EA stimulation.
While GluR-1-LI neuron of 15 Hz and 120 Hz EA was increased in the nucleus proprius compared with carrageenan-
injected group, GluR-2/3-LI neuron of these EA stimulated groups significantly reduced in superficial laminae
of dorsal horn. In conclusion, EA treatment can attenuate spinal c-fos expression in carrageenan injected rats and
regulates spinal inotropic glutamate receptor expression.
KW - : Electroacupucture;Spinal cord;c-fos;NMDA;AMPA
DO - 10.11637/aba.2004.17.1.11
ER -
이준혁, Yung Hyun Choi and 최병태. (2004). Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat. Anatomy & Biological Anthropology, 17(1), 11-18.
이준혁, Yung Hyun Choi and 최병태. 2004, "Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat", Anatomy & Biological Anthropology, vol.17, no.1 pp.11-18. Available from: doi:10.11637/aba.2004.17.1.11
이준혁, Yung Hyun Choi, 최병태 "Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat" Anatomy & Biological Anthropology 17.1 pp.11-18 (2004) : 11.
이준혁, Yung Hyun Choi, 최병태. Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat. 2004; 17(1), 11-18. Available from: doi:10.11637/aba.2004.17.1.11
이준혁, Yung Hyun Choi and 최병태. "Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat" Anatomy & Biological Anthropology 17, no.1 (2004) : 11-18.doi: 10.11637/aba.2004.17.1.11
이준혁; Yung Hyun Choi; 최병태. Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat. Anatomy & Biological Anthropology, 17(1), 11-18. doi: 10.11637/aba.2004.17.1.11
이준혁; Yung Hyun Choi; 최병태. Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat. Anatomy & Biological Anthropology. 2004; 17(1) 11-18. doi: 10.11637/aba.2004.17.1.11
이준혁, Yung Hyun Choi, 최병태. Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat. 2004; 17(1), 11-18. Available from: doi:10.11637/aba.2004.17.1.11
이준혁, Yung Hyun Choi and 최병태. "Effects of electroacupuncture with different frequencies on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rat" Anatomy & Biological Anthropology 17, no.1 (2004) : 11-18.doi: 10.11637/aba.2004.17.1.11
