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@article{ART001143845},
author={임정민 and 이광소 and Chai Ok Hee and Song Chang Ho},
title={Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2004},
volume={17},
number={1},
pages={19-30},
doi={10.11637/aba.2004.17.1.19}

TY - JOUR
AU - 임정민
AU - 이광소
AU - Chai Ok Hee
AU - Song Chang Ho
TI - Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability
JO - Anatomy & Biological Anthropology
PY - 2004
VL - 17
IS - 1
PB - 대한체질인류학회
SP - 19
EP - 30
SN - 2671-5651
AB - The fruit of Corni fructus (CF), a perennial herb, is believed to have anti-allergy effects, but its mechanism is unknown. The purpose of this study is to investigate the inhibitory effect of CF on compound 48/80-induced mast cell activation. For this, the effects of CF on the degranulation, the histamine release, the calcium influx and the change of the intracellular cAMP levels of rat peritoneal mast cells (RPMC) and influences of CF on the compound 48/80-induced cutaneous reaction were studied. The results were as follows; the compound 48/80-induced degranulation, intracelluar calcium influx and histamine release of RPMC was significantly inhibited by pretreatment with CF, the compound 48/80 -induced cAMP level of RPMC were significantly increased by pretreatment with CF, CF significantly inhibited compound 48/80-induced vascular permeability of rat cutaneous tissue. From the above results, it is suggested that CF contains some substances which inhibit the compound 48/80-induced vascular permeability and mast cell activation.
KW - Mast cell;Corni fructus;Compound 48/80;Histmaine;Calcium;cAMP
DO - 10.11637/aba.2004.17.1.19
ER -

임정민, 이광소, Chai Ok Hee and Song Chang Ho. (2004). Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability. Anatomy & Biological Anthropology, 17(1), 19-30.

임정민, 이광소, Chai Ok Hee and Song Chang Ho. 2004, "Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability", Anatomy & Biological Anthropology, vol.17, no.1 pp.19-30. Available from: doi:10.11637/aba.2004.17.1.19

임정민, 이광소, Chai Ok Hee, Song Chang Ho "Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability" Anatomy & Biological Anthropology 17.1 pp.19-30 (2004) : 19.

임정민, 이광소, Chai Ok Hee, Song Chang Ho. Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability. 2004; 17(1), 19-30. Available from: doi:10.11637/aba.2004.17.1.19

임정민, 이광소, Chai Ok Hee and Song Chang Ho. "Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability" Anatomy & Biological Anthropology 17, no.1 (2004) : 19-30.doi: 10.11637/aba.2004.17.1.19

임정민; 이광소; Chai Ok Hee; Song Chang Ho. Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability. Anatomy & Biological Anthropology, 17(1), 19-30. doi: 10.11637/aba.2004.17.1.19

임정민; 이광소; Chai Ok Hee; Song Chang Ho. Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability. Anatomy & Biological Anthropology. 2004; 17(1) 19-30. doi: 10.11637/aba.2004.17.1.19

임정민, 이광소, Chai Ok Hee, Song Chang Ho. Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability. 2004; 17(1), 19-30. Available from: doi:10.11637/aba.2004.17.1.19

임정민, 이광소, Chai Ok Hee and Song Chang Ho. "Inhibitory effect of Corni fructus on compound 48/80-induced mast cell activation and vascular permeability" Anatomy & Biological Anthropology 17, no.1 (2004) : 19-30.doi: 10.11637/aba.2004.17.1.19