Localization Patterns of Cytokeratin 1, 14 and PAX 9 in Mouse Embryonic Tongue Development (생쥐 배아 혀 상피의 발생과정에서 나타나는 사이토케라틴 1, 14와 PAX 9에 관한 면역조직화학적 연구)

정혜인; JIN, MYOUNG UK (진명욱); Je Yoel Cho (조제열); HAN-SUNG JUNG (정한성); 김재영

doi:10.11637/aba.2008.21.4.293

Localization Patterns of Cytokeratin 1, 14 and PAX 9 in Mouse Embryonic Tongue Development

Anatomy & Biological Anthropology
Abbr : Anat Biol Anthropol
2008, 21(4), pp.293~303
DOI : 10.11637/aba.2008.21.4.293
Publisher : 대한체질인류학회
Research Area : Medicine and Pharmacy > Anatomy

정혜인 ¹, JIN, MYOUNG UK ¹, Je Yoel Cho ², HAN-SUNG JUNG ³, 김재영 ¹

¹경북대학교
²서울대학교
³연세대학교

Accredited

ABSTRACT

Epithelial differentiation and morphogenesis in skin and oral mucosa were elucidated using various experimental tools. However, tongue epithelial differentiation has not been examined properly yet. In this study, we identified the relationship between morphological changes and localizations of differentiation markers, such as cytokeratins and PAX 9 in mice embryonic tongue development. Protective barrier formation and localization pattern of cytokeratins in tongue epithelium were examined with toluidine blue staining and immunohistochemistry respectively. Localization patterns of PAX 9 and Cytokeratin 14 were coincided during tongue epithelium development. In addition, compared with Ki67 localizations, marker for cell proliferation, localization patterns of PAX 9 and Cytokeratin 14 would suggest that these factors would involve in tongue barrier formation through cell proliferation. Based on these results, tongue epithelial differentiation woule begin at E14 with the specific localizations of PAX 9 and Cytokeratin 14 prior to protective barrier formation then Cytokeratin 1, keratinization marker, would involve in protective barrier and filiform papillae formations.

KEYWORDS

Tongue epithelium, Development, Protective barrier, Cytokeratin, PAX 9, Proliferation, Differentiation

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Anatomy & Biological Anthropology 2023 KCI Impact Factor : 0.33

Localization Patterns of Cytokeratin 1, 14 and PAX 9 in Mouse Embryonic Tongue Development

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* References for papers published after 2023 are currently being built.

Anatomy & Biological Anthropology 2023 KCI Impact Factor : 0.33

Localization Patterns of Cytokeratin 1, 14 and PAX 9 in Mouse Embryonic Tongue Development

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