@article{ART001404598},
author={마스키 디라즈 and 유영복 and 최인영 and 박기섭 and 프라단 조누},
title={The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2009},
volume={22},
number={4},
pages={295-304},
doi={10.11637/aba.2009.22.4.295}
TY - JOUR
AU - 마스키 디라즈
AU - 유영복
AU - 최인영
AU - 박기섭
AU - 프라단 조누
TI - The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex
JO - Anatomy & Biological Anthropology
PY - 2009
VL - 22
IS - 4
PB - 대한체질인류학회
SP - 295
EP - 304
SN - 2671-5651
AB - Widespread use of mobile phones and subsequent electromagnetic field (EMF) exposure have raised crucial question of their possible biological effects on the nervous system. The study on the effect of radiofrequency(RF) radiation on the nervous system, however, did not precede enough to determine the biological hazard to brain. Until now, several studies have reported decreases in neuron number and neuronal damage in the cortex, hippocampus, and basal ganglia in the brains of animals exposed to RF radiation. However, there were few reports about the cerebellum, the main voluntary motor control center. In this regard, by using immunohistochemisty, current study intended to investigate the changes in the calbindin D28k (CB) and calretinin (CR)-immunoreactivity (IR) in the mouse cerebellar cortex after EMF exposure at 835 MHz for different exposure times and absorption rates, 1 h/day for 5 days at 1.6 W/kg, 1 h/day for 5 days at 4.0 W/kg, 5 h/day for 1 day at 1.6 W/kg, 5 h/day for 1 day at 4.0 W/kg, daily exposure for one month at 1.6 W/kg. Among groups, most prominent CB IR was observed in the Purkinje cell layer followed by molecular and granular layer. The highest CB IR was noted in 5 h/day for 1 day at 1.6 W/kg in the entire three layers while the lowest was noted in one month at 1.6 W/kg. Similarly CR IR was maximum in one month at 1.6 W/kg whilst the lowest was observed in 1 h/day for 5 days at 4.0 W/kg. EMF exposure for 5 days at 1.6 W/kg reduced CB-IR. The CR-IR was mainly localized in small cells in the granular layer, with maximum IR observed after one month exposure. Therefore, the present study suggest the possibility of alterations of calcium ion concentration, which play a role in maintaining metabolic homeostasis, in the cerebellum after long-term exposure to 835 MHz of RF radiation, which might lead to the disruption of normal trait.
KW - 전자기파;Calbindin D28k;Calretinin;칼슘;소뇌
DO - 10.11637/aba.2009.22.4.295
ER -
마스키 디라즈, 유영복, 최인영, 박기섭 and 프라단 조누. (2009). The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex. Anatomy & Biological Anthropology, 22(4), 295-304.
마스키 디라즈, 유영복, 최인영, 박기섭 and 프라단 조누. 2009, "The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex", Anatomy & Biological Anthropology, vol.22, no.4 pp.295-304. Available from: doi:10.11637/aba.2009.22.4.295
마스키 디라즈, 유영복, 최인영, 박기섭, 프라단 조누 "The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex" Anatomy & Biological Anthropology 22.4 pp.295-304 (2009) : 295.
마스키 디라즈, 유영복, 최인영, 박기섭, 프라단 조누. The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex. 2009; 22(4), 295-304. Available from: doi:10.11637/aba.2009.22.4.295
마스키 디라즈, 유영복, 최인영, 박기섭 and 프라단 조누. "The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex" Anatomy & Biological Anthropology 22, no.4 (2009) : 295-304.doi: 10.11637/aba.2009.22.4.295
마스키 디라즈; 유영복; 최인영; 박기섭; 프라단 조누. The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex. Anatomy & Biological Anthropology, 22(4), 295-304. doi: 10.11637/aba.2009.22.4.295
마스키 디라즈; 유영복; 최인영; 박기섭; 프라단 조누. The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex. Anatomy & Biological Anthropology. 2009; 22(4) 295-304. doi: 10.11637/aba.2009.22.4.295
마스키 디라즈, 유영복, 최인영, 박기섭, 프라단 조누. The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex. 2009; 22(4), 295-304. Available from: doi:10.11637/aba.2009.22.4.295
마스키 디라즈, 유영복, 최인영, 박기섭 and 프라단 조누. "The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex" Anatomy & Biological Anthropology 22, no.4 (2009) : 295-304.doi: 10.11637/aba.2009.22.4.295
