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Microscopic Observation of Decomposition-inhibition Effect in GSE (Grapefruit Seed Extract) in Rat Liver

Kyusung Hwang 1 임도선 ORD ID 1 Ki-Ju Choi 2 서윤경 3 Paik Doo Jin 3

1을지대학교
2을지대학교 전자현미경실
3한양대학교

Accredited

ABSTRACT

Regarding to preserve the cadaver, formaldehyde has been used as a major preservative. However, the usage of formaldehyde has been considered by its harmful effects such as the disturbing ordor, toxicities and limitations to use. Therefore we studied the effect of decomposition-inhibition which is a natural product, grapefruit seed extract (GSE). Concerning the preservative activity, we sacrificed 8 week old male SD rat and collected liver. Using liver tissues,we treated GSE as a time dependant manner under 37􀆆C, 80±5% humidity conditions. To confirm GSE effects,we applied light and electron microscopic analysis. In results, we observed GSE attenuated the morphological changes and putrefaction of liver tissues more than 3days. Herein, we introduced the potential substitute of formaldehyde to preserve the cadaver as well as animal tissues.

Citation status

* References for papers published after 2024 are currently being built.