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@article{ART001913298},
author={Lee, Jae-Ho and KIM, DAE-KWANG},
title={Association between Mitochondrial D-loop Polymorphism and Copy Number},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2014},
volume={27},
number={3},
pages={131-136},
doi={10.11637/aba.2014.27.3.131}

TY - JOUR
AU - Lee, Jae-Ho
AU - KIM, DAE-KWANG
TI - Association between Mitochondrial D-loop Polymorphism and Copy Number
JO - Anatomy & Biological Anthropology
PY - 2014
VL - 27
IS - 3
PB - 대한체질인류학회
SP - 131
EP - 136
SN - 2671-5651
AB - Mitochondria in cancer have genetic instability like genetic mutations or polymorphisms, and D-loopis hot spot region and is suggested its association with cancer prognosis. Genetic variations of D-loop were associatedwith mitochondrial copy number. In present study, mitochondrial polymorphism in D-loop (D310 and D514)was studied in 108 DNAs from health individuals and its association with mitochondrial copy number was alsoinvestigated. In D310 polymorphism, C7 was most common (37.7%, 40/108), and C8 and C9 was found in 32.1%and 30.2%, respectively. In D514 polymorphism, (CA)5 and (CA)4 was shown in 61.4% and 38.6%, respectively. Mitochondrial copy number was increased in 40.7% while it was decreased in 59.3%. There was no associationbetween mitochondrial polymorphism and copy number. Follow-up study should be needed to confirm its changein same individuals.
KW - Mitochondrial polymorphism;Mitochondrial copy number;D-loop
DO - 10.11637/aba.2014.27.3.131
ER -

Lee, Jae-Ho and KIM, DAE-KWANG. (2014). Association between Mitochondrial D-loop Polymorphism and Copy Number. Anatomy & Biological Anthropology, 27(3), 131-136.

Lee, Jae-Ho and KIM, DAE-KWANG. 2014, "Association between Mitochondrial D-loop Polymorphism and Copy Number", Anatomy & Biological Anthropology, vol.27, no.3 pp.131-136. Available from: doi:10.11637/aba.2014.27.3.131

Lee, Jae-Ho, KIM, DAE-KWANG "Association between Mitochondrial D-loop Polymorphism and Copy Number" Anatomy & Biological Anthropology 27.3 pp.131-136 (2014) : 131.

Lee, Jae-Ho, KIM, DAE-KWANG. Association between Mitochondrial D-loop Polymorphism and Copy Number. 2014; 27(3), 131-136. Available from: doi:10.11637/aba.2014.27.3.131

Lee, Jae-Ho and KIM, DAE-KWANG. "Association between Mitochondrial D-loop Polymorphism and Copy Number" Anatomy & Biological Anthropology 27, no.3 (2014) : 131-136.doi: 10.11637/aba.2014.27.3.131

Lee, Jae-Ho; KIM, DAE-KWANG. Association between Mitochondrial D-loop Polymorphism and Copy Number. Anatomy & Biological Anthropology, 27(3), 131-136. doi: 10.11637/aba.2014.27.3.131

Lee, Jae-Ho; KIM, DAE-KWANG. Association between Mitochondrial D-loop Polymorphism and Copy Number. Anatomy & Biological Anthropology. 2014; 27(3) 131-136. doi: 10.11637/aba.2014.27.3.131

Lee, Jae-Ho, KIM, DAE-KWANG. Association between Mitochondrial D-loop Polymorphism and Copy Number. 2014; 27(3), 131-136. Available from: doi:10.11637/aba.2014.27.3.131

Lee, Jae-Ho and KIM, DAE-KWANG. "Association between Mitochondrial D-loop Polymorphism and Copy Number" Anatomy & Biological Anthropology 27, no.3 (2014) : 131-136.doi: 10.11637/aba.2014.27.3.131