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Application of Developmental Principles for Functional Regeneration of Salivary Glands

  • Anatomy & Biological Anthropology
  • Abbr : Anat Biol Anthropol
  • 2019, 32(3), pp.83~91
  • DOI : 10.11637/aba.2019.32.3.83
  • Publisher : 대한체질인류학회
  • Research Area : Medicine and Pharmacy > Anatomy
  • Received : April 25, 2019
  • Accepted : August 20, 2019
  • Published : September 30, 2019

Eui-Seon Lee 1 Nirpesh Adhikari 2 정재광 2 Chang-Hyeon An 2 KIM, JAE-YOUNG 2 KimJi-Youn 3

1경북대학교 치과대학 생화학교실
2경북대학교
3가천대학교

Accredited

ABSTRACT

Currently, there has been rapid increase in the studies about salivary production because of the hyposalivation, xerostomia, caused by radiotherapy for head and neck cancer, Sjogren syndrome and aging. An overview of anatomy and development of salivary gland is crucial to understand about the patho-physiological disorders related with saliva. For study of the morphogenesis and development of salivary glands, experiment using rodent models is widely necessary. This review wraps up the early to latest studies - the different features of each salivary gland, morphogenesis of developing salivary glands, and the comparison of human and rodent salivary glands. The goal of this review is to provide hypothesis for the further researches about differentiation of specific acinar cells, from which it is determined to be specific acini. Additionally, we discuss approaches to regenerate the function of salivary glands using environmental factor, time dependent factor and nerve factor.

Citation status

* References for papers published after 2023 are currently being built.

This paper was written with support from the National Research Foundation of Korea.