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Diagnostic Usefulness of Degenerative Disc Disease Using the CT Number

  • Anatomy & Biological Anthropology
  • Abbr : Anat Biol Anthropol
  • 2024, 37(3), pp.141~150
  • DOI : 10.11637/aba.2024.37.3.141
  • Publisher : 대한체질인류학회
  • Research Area : Medicine and Pharmacy > Anatomy
  • Received : August 23, 2024
  • Accepted : September 25, 2024
  • Published : September 30, 2024

Tai-Soo Park 1 Yoon, Sik 2

1대구우리들병원 영상의학과
2부산대학교 의과대학 해부학교실

Accredited

ABSTRACT

This study aimed to determine the prevalence of each grade of degenerative disc disease (DDD) and to measure the height and computed tomography (CT) numbers of intervertebral discs in affected regions. A total of 412 patients (221 males and 191 females) who underwent magnetic resonance imaging (MRI) for back pain were included in the study. DDD grades were classified, and disc heights were measured using three images from the lumbosacral region. The CT number, measured in Hounsfield unit (HU), for DDD was obtained using CT scans. The average age of the subjects was 49.47 years. In the disc between the 3rd and 4th lumbar vertebrae, no significant difference in degenerative grades was found between genders. However, in the disc between the 4th and 5th vertebrae, grade 3 was observed in 21.47% of male subjects, while grade 4 was found in 24.3% of female subjects (p<0.001). Additionally, in the disc between the 5th lumbar vertebra and the 1st sacral vertebra, grade 4 was the most common degenerative grade in both males (98 cases, 23.8%) and females (113 cases, 27.4%), with a significant difference between genders (p<0.05). Regarding intervertebral disc height, discs in grade 1 measured 10.71 ± 1.47 mm, those in grade 2 measured 9.95 ± 1.35 mm, in grade 3 measured 9.65 ± 1.62 mm, in grade 4 measured 8.70 ± 1.74 mm, and in grade 5 measured 6.52 ± 1.89 mm. This shows a trend of decreasing disc height as the degeneration grade increased (p<0.001). Furthermore, the CT numbers according to the degenerative grade were 57.34 ± 4.66 HU in grade 1, 67.64 ± 3.97 HU in grade 2, 75.75 ± 3.90 HU in grade 3, 86.51 ± 6.14 HU in grade 4, and 112.48 ± 10.89 HU in grade 5, all showing significant differences (p<0.001). Based on the results of this study, disc height and CT numbers (HU) could be clinically useful indicators for assessing the degree of DDD in Koreans.

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