Mechanical properties of polycaprolactone bone scaffolds reinforced with carbon nanotube-modified tricalcium phosphate

Wenjun Yang; Chenchen Li; Lu Han

doi:10.1007/s42823-024-00788-0

Mechanical properties of polycaprolactone bone scaffolds reinforced with carbon nanotube-modified tricalcium phosphate

Carbon Letters
Abbr : Carbon Lett.
2025, 35(1), pp.267~276
DOI : 10.1007/s42823-024-00788-0
Publisher : Korean Carbon Society
Research Area : Natural Science > Natural Science General > Other Natural Sciences General
Received : April 3, 2024
Accepted : August 4, 2024
Published : March 28, 2025

Wenjun Yang ¹, Chenchen Li ¹, Lu Han ¹

¹The Third Affiliated Hospital of Jinzhou Medical University

Accredited

ABSTRACT

Three-dimensional printed polycaprolactone/β-tricalcium phosphate (PCL/β-TCP) scaffolds reinforced with carbon nanotubes (CNTs) were fabricated and characterized for bone tissue engineering applications. The incorporation of CNTs significantly enhanced the mechanical properties, with the aligned PCL/β-TCP/CNT scaffold (1 wt% CNTs) exhibiting a 125% and 123% increase in compressive modulus (180.3 ± 10.1 MPa) and strength (7.8 ± 0.6 MPa), respectively, compared to the PCL/β-TCP scaffold. The β-glycerol phosphate (BGP)-modified PCL/β-TCP/CNT scaffold showed similar mechanical properties to the aligned scaffold. All scaffolds maintained high porosity (> 70%) and a wide pore size distribution (50–500 μm). The scaffolds demonstrated excellent biocompatibility, with hemolysis rates below 5% and high cell viability. The aligned PCL/β-TCP/CNT scaffold promoted the highest rat adipose-derived stem cell proliferation, while the BGP-modified scaffold enhanced human dental pulp stem cell proliferation and mineralization.

KEYWORDS

3D printing, Biocompatibility, Stem cells, Mineralization, Tissue regeneration

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Carbon Letters 2025 KCI Impact Factor : 0.73 KCI-WoS Impact Factor : 6.26

Mechanical properties of polycaprolactone bone scaffolds reinforced with carbon nanotube-modified tricalcium phosphate

ABSTRACT

KEYWORDS

Citation status

This is the result of checking the information with the same ISSN, publication year, volume, and start page between the WoS and the KCI journals. (as of 2026-07-09)

Total Citation Counts(KCI+WOS) (22) This is the number of times that the duplicate count has been removed by comparing the citation list of WoS and KCI.

* References for papers published after 2025 are currently being built.

Carbon Letters 2025 KCI Impact Factor : 0.73 KCI-WoS Impact Factor : 6.26

Mechanical properties of polycaprolactone bone scaffolds reinforced with carbon nanotube-modified tricalcium phosphate

ABSTRACT

KEYWORDS

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WoS Citation Counts (21) This is the result of checking the information with the same ISSN, publication year, volume, and start page between the WoS and the KCI journals. (as of 2026-07-09)

Total Citation Counts(KCI+WOS) (22) This is the number of times that the duplicate count has been removed by comparing the citation list of WoS and KCI.

REFERENCES (31) * References for papers published after 2025 are currently being built.

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This is the result of checking the information with the same ISSN, publication year, volume, and start page between the WoS and the KCI journals. (as of 2026-07-09)

* References for papers published after 2025 are currently being built.