@article{ART002029149},
author={Lay-Jing Seow and Hooi-Kheng Beh and Amirin Sadikun and Mohd. Zaini Asmawi},
title={Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum},
journal={CELLMED},
issn={3022-6805},
year={2014},
volume={4},
number={1},
pages={4-4},
doi={10.5667/tang.2013.0035}
TY - JOUR
AU - Lay-Jing Seow
AU - Hooi-Kheng Beh
AU - Amirin Sadikun
AU - Mohd. Zaini Asmawi
TI - Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum
JO - CELLMED
PY - 2014
VL - 4
IS - 1
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 4
EP - 4
SN - 3022-6805
AB - Gynura segetum, family Asteraceae is a cultivated species and can be found growing in the tropical regions of Indonesia and Malaysia. The plant is known for its use for the treatment of cancer, inflammation, diabetes, hypertension and skin afflictions. In the current study, anti-inflammatory effect of Gynura segetum leaf has been investigated. The present study investigated the in vivo anti-inflammatory effect of Gynura segetum leaf by using hen’s egg test-chorioallantoic membrane (HET-CAM) assay. Different solvent extract of Gynura segetum leaf were tested, the most active methanol extract was further fractionated and tested. Among the extracts tested, the methanol extract showed a significant good anti-inflammatory effect (76.8% inhibition at 50 µg/disc) on the HET-CAM assay as compared with the anti-inflammatory drug indomethacin (82.1% inhibition). However, the fractionated sample exhibited a significantly lower activity in comparison to crude methanol extract. The results demonstrated that Gynura segetum leaf displayed remarkable anti-inflammatory effects, which support the folkloric uses of this plant for treatment of inflammation.
KW - Gynura segetum;Asteraceae;HET-CAM;anti-inflammatory
DO - 10.5667/tang.2013.0035
ER -
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun and Mohd. Zaini Asmawi. (2014). Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum. CELLMED, 4(1), 4-4.
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun and Mohd. Zaini Asmawi. 2014, "Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum", CELLMED, vol.4, no.1 pp.4-4. Available from: doi:10.5667/tang.2013.0035
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun, Mohd. Zaini Asmawi "Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum" CELLMED 4.1 pp.4-4 (2014) : 4.
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun, Mohd. Zaini Asmawi. Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum. 2014; 4(1), 4-4. Available from: doi:10.5667/tang.2013.0035
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun and Mohd. Zaini Asmawi. "Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum" CELLMED 4, no.1 (2014) : 4-4.doi: 10.5667/tang.2013.0035
Lay-Jing Seow; Hooi-Kheng Beh; Amirin Sadikun; Mohd. Zaini Asmawi. Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum. CELLMED, 4(1), 4-4. doi: 10.5667/tang.2013.0035
Lay-Jing Seow; Hooi-Kheng Beh; Amirin Sadikun; Mohd. Zaini Asmawi. Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum. CELLMED. 2014; 4(1) 4-4. doi: 10.5667/tang.2013.0035
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun, Mohd. Zaini Asmawi. Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum. 2014; 4(1), 4-4. Available from: doi:10.5667/tang.2013.0035
Lay-Jing Seow, Hooi-Kheng Beh, Amirin Sadikun and Mohd. Zaini Asmawi. "Evaluation of anti-inflammatory effect of traditional medicinal plants, Gynura segetum" CELLMED 4, no.1 (2014) : 4-4.doi: 10.5667/tang.2013.0035
