@article{ART002175891},
author={Hyun-Ja Jeong and Sun-Young Nam},
title={Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication},
journal={CELLMED},
issn={3022-6805},
year={2013},
volume={3},
number={1},
pages={3-3}
TY - JOUR
AU - Hyun-Ja Jeong
AU - Sun-Young Nam
TI - Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication
JO - CELLMED
PY - 2013
VL - 3
IS - 1
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 3
EP - 3
SN - 3022-6805
AB - The receptor activator of NF-κB ligand (RANKL), a member of the tumor necrosis factor ligand family, has extensive functions beyond osteoclast development. RANKL is expressed in many immune cells such as osteoblasts, osteocytes, marrow stromal cells, activated T cells, synovial cells, keratinocytes, and mammary gland epithelial cells as well as in various tissues. The ligation of RANK by RANKL promotes dendritic cells (DCs) survival through prosurvival signals and the up-regulation of the anti-apoptotic proteins Bcl-2 and Bcl-xL and plays a crucial role in DCs-mediated Th1 differentiation. Therefore, RANKL plays an important role in the regulation of DCs/T cells-mediated specific immunity. This review will briefly inform our current understanding of the role of RANKL signaling in T cells-DCs communication in the immune system.
KW - RANKL;dendritic cells;T cells;differentiation;immunity
DO -
UR -
ER -
Hyun-Ja Jeong and Sun-Young Nam. (2013). Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication. CELLMED, 3(1), 3-3.
Hyun-Ja Jeong and Sun-Young Nam. 2013, "Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication", CELLMED, vol.3, no.1 pp.3-3.
Hyun-Ja Jeong, Sun-Young Nam "Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication" CELLMED 3.1 pp.3-3 (2013) : 3.
Hyun-Ja Jeong, Sun-Young Nam. Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication. 2013; 3(1), 3-3.
Hyun-Ja Jeong and Sun-Young Nam. "Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication" CELLMED 3, no.1 (2013) : 3-3.
Hyun-Ja Jeong; Sun-Young Nam. Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication. CELLMED, 3(1), 3-3.
Hyun-Ja Jeong; Sun-Young Nam. Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication. CELLMED. 2013; 3(1) 3-3.
Hyun-Ja Jeong, Sun-Young Nam. Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication. 2013; 3(1), 3-3.
Hyun-Ja Jeong and Sun-Young Nam. "Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication" CELLMED 3, no.1 (2013) : 3-3.