@article{ART002196499},
author={Hyun-Ja Jeong and 문아림 and 김나형 and 정차권},
title={Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test},
journal={CELLMED},
issn={3022-6805},
year={2017},
volume={7},
number={1},
pages={4-4}
TY - JOUR
AU - Hyun-Ja Jeong
AU - 문아림
AU - 김나형
AU - 정차권
TI - Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test
JO - CELLMED
PY - 2017
VL - 7
IS - 1
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 4
EP - 4
SN - 3022-6805
AB - Sogeunjung-tang (S-tang) is a traditional Korean medicine that has been used for the therapy of anxiety disorder in a variety of clinical situations. However, no study has investigated this effect. The aim of this study was to investigate the effectiveness of S-tang for reducing depression in animal model. The anti-depressant effect of S-tang was investigated in ICR mice by using forced swimming test (FST). After FST, we analyzed the blood biochemical parameters from blood. The immobility time was significantly decreased in the S-tang oral administration or pharmaceutical acupuncture group compared with the control group at 14 days (p < 0.05). The anti-depressant effect of S-tang was higher than that of fluoxetine (a classical anti-depressant). S-tang or fluoxetine significantly decreased the creatine kinase and lactate dehydrogenase level compared with the control group (p < 0.05) but not glucose, protein, and blood urea nitrogen level. Further investigation of S-tang as a potential pharmacologic agent in the management of depression related anxiety is warranted.
KW - Sogeunjung-tang;forced swimming test;immobility time;depression
DO -
UR -
ER -
Hyun-Ja Jeong, 문아림, 김나형 and 정차권. (2017). Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test. CELLMED, 7(1), 4-4.
Hyun-Ja Jeong, 문아림, 김나형 and 정차권. 2017, "Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test", CELLMED, vol.7, no.1 pp.4-4.
Hyun-Ja Jeong, 문아림, 김나형, 정차권 "Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test" CELLMED 7.1 pp.4-4 (2017) : 4.
Hyun-Ja Jeong, 문아림, 김나형, 정차권. Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test. 2017; 7(1), 4-4.
Hyun-Ja Jeong, 문아림, 김나형 and 정차권. "Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test" CELLMED 7, no.1 (2017) : 4-4.
Hyun-Ja Jeong; 문아림; 김나형; 정차권. Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test. CELLMED, 7(1), 4-4.
Hyun-Ja Jeong; 문아림; 김나형; 정차권. Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test. CELLMED. 2017; 7(1) 4-4.
Hyun-Ja Jeong, 문아림, 김나형, 정차권. Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test. 2017; 7(1), 4-4.
Hyun-Ja Jeong, 문아림, 김나형 and 정차권. "Sogeunjung-tang improves depressive-like behavior decreased by forced-swimming test" CELLMED 7, no.1 (2017) : 4-4.
