Phytochemical Standardization and Anti-Anxiety (Izterab-e-Nafsani) study of Aftimoon Hindi (Cuscuta reflexa Roxb.) on An Animal Model

Irfat Ara; Mohd Afsahul Kalam; Mudasir Maqbool; Mehrukh Zehravi

doi:10.5667/CellMed.2021.0014

Phytochemical Standardization and Anti-Anxiety (Izterab-e-Nafsani) study of Aftimoon Hindi (Cuscuta reflexa Roxb.) on An Animal Model

CELLMED
Abbr : CellMed
2021, 11(3), pp.14-14
DOI : 10.5667/CellMed.2021.0014
Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
Research Area : Medicine and Pharmacy > General Medicine
Received : May 24, 2021
Accepted : August 10, 2021
Published : August 31, 2021

Irfat Ara ¹, Mohd Afsahul Kalam ¹, Mudasir Maqbool ², Mehrukh Zehravi ³

¹Regional Research Institute of Unani Medicine, University of Kashmir
²Department of Pharmaceutical Sciences, University of Kashmir
³Department of Clinical Pharmacy Girls Section, Prince Sattam Bin Abdul Aziz University Alkharj

Accredited

ABSTRACT

Background: Cuscuta reflexa Roxb is a member of the Cuscutaceae family, and in Unani medicine, it is known as Aftimoon. It is a parasitic plant that can be found growing abundantly on various host plants in India up to 3000 metres in altitude during the rainy season. Unani physicians have been using it for years to cure a variety of illnesses, including psychiatric illnesses like melancholia, schizophrenia, and epilepsy. It has been used to cure hepatitis, palpitations, and skin disorders, among other things. Objective of the study: To evaluate anti-anxiety effect of Cuscuta reflexa Roxb in Swiss Albino mice of either sex. Materials and Methods: A total of 24 Swiss Albino mice weighing 25-35 g were used in this study. Animals were chosen at random and held in their cages for at least 7 days in a standard setting. Group A was given regular saline as a vehicle, Group B was given a hydro alcoholic extract of the lower dose of the test drug, Group C was given a hydro alcoholic extract of the higher dose of the test drug, and Group D was given the standard drug Diazepam 5 mg/kg orally. Aftimoon as hydro alcoholic extract (200 mg/kg and 400 mg/kg body wt.) was given in single and double doses and observed for 7 days. Results: For each parameter in each category, mean and standard deviations were computed. For multiple group comparisons, a one-way ANOVA was used, followed by Turkey's post hoc test. (p<0.05) was used as the significance standard. Conclusion: These results advocate that the Aftimoon as double dose (400 mg/kg body wt.) revealed anti-anxiety effect similar to standard drug.

KEYWORDS

Aftimoon Hindi. Anxiety Disorder. Izterab-e- Nafsani. Unani Medicine

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Phytochemical Standardization and Anti-Anxiety (Izterab-e-Nafsani) study of Aftimoon Hindi (Cuscuta reflexa Roxb.) on An Animal Model

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* References for papers published after 2023 are currently being built.

CELLMED 2023 KCI Impact Factor : 0.03

Phytochemical Standardization and Anti-Anxiety (Izterab-e-Nafsani) study of Aftimoon Hindi (Cuscuta reflexa Roxb.) on An Animal Model

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