Cognitive Improvement Effect of Resplex Alpha A in the Scopolamine-induced Mouse Model

Bong-Keun Jang (장봉근); Young-Sun Kwon (권영선); Sun-Young Park (박선영); Gun-Woo Lee (이건우); Hye-Yeoun Kang (강혜연); Jeom-Yong Kim (김점용)

doi:10.5667/CellMed.2023.014

Cognitive Improvement Effect of Resplex Alpha A in the Scopolamine-induced Mouse Model

CELLMED
Abbr : CellMed
2023, 13(14), pp.1~1
DOI : 10.5667/CellMed.2023.014
Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
Research Area : Medicine and Pharmacy > General Medicine
Received : November 30, 2023
Accepted : November 30, 2023
Published : November 30, 2023

Bong-Keun Jang ¹, Young-Sun Kwon ¹, Sun-Young Park ¹, Gun-Woo Lee ¹, Hye-Yeoun Kang ¹, Jeom-Yong Kim ¹

¹JBK-LAB, Inc.

Accredited

ABSTRACT

Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).

KEYWORDS

Resveratrol-alginate nano-complex (RANCP), Ginkgo biloba extract (EGb231), Cognitive function, Memory dysfunction, Alzheimer’s disease (AD), dementia

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