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Effect of surface-treatments on flexibility and guided bone regeneration of titanium barrier membrane

  • Journal of the Korean Crystal Growth and Crystal Technology
  • Abbr : J. Korean Cryst. Growth Cryst. Technol.
  • 2015, 25(3), pp.98-104
  • DOI : 10.6111/JKCGCT.2015.25.3.098
  • Publisher : The Korea Association Of Crystal Growth, Inc.
  • Research Area : Engineering > Materials Science and Engineering

김진태 1 김병수 1 Jeong heeseok 1 Young-Ku Heo 1 신상원 2 이정렬 2 심영호 2 DeukYong Lee ORD ID 3

1네오바이오텍
2고려대학교
3대림대학교

Accredited

ABSTRACT

Titanium barrier membranes are prepared to investigate the effect of surface-treatments, such as machining, electropolishing, anodizing, and electropolishing + TiN coating, on the biocompatibility and physical properties of the membranes. The surface roughness (Ra) of the membrane decreases from machining (0.37 ± 0.09 μm), TiN coating (0.22 ± 0.09 μm), electropolishing (0.20 ± 0.03 μm), to anodizing (0.15 ± 0.03 μm). The highest ductility (24.50 %) is observed for the electropolished Ti membrane. No evidence of causing cell lysis or toxicity is found for the membranes regardless of the surface-treatments. Cell adhesion results of L-929 and MG-63 show that the machined Ti membrane exhibits the highest cell adhesion while the electropolished membrane is the best membrane for the L-929 cell proliferation after 7 days. However, no appreciable difference in MG-63 cell proliferation among variously surface-treated membranes is detected, suggesting that the electropolished Ti membrane is likely to be the best membrane due to the synergic combination of tailored flexibility and excellent fibroblast proliferation.

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