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Preparation and characterization of silanized-hydroxypropyl methylcellulose/ phase transformed calcium phosphate composite bone cements

  • Journal of the Korean Crystal Growth and Crystal Technology
  • Abbr : J. Korean Cryst. Growth Cryst. Technol.
  • 2016, 26(6), pp.243~251
  • DOI : 10.6111/JKCGCT.2016.26.6.243
  • Publisher : The Korea Association Of Crystal Growth, Inc.
  • Research Area : Engineering > Materials Science and Engineering
  • Received : November 7, 2016
  • Accepted : November 21, 2016
  • Published : December 31, 2016

Nahyun Jeong 1 Dong-Hyun Kim 2 Hoon-Sang Cho 3 Seog-Young Yoon 1

1부산대학교
2유펙스 · 메드 기술개발부
3유펙스 · 메드 기술개발부,

Accredited

ABSTRACT

Silanized-hydroxypropyl methylcellulose (Si-HPMC)/phase transformed calcium phosphate (PTCP) composites are prepared to purpose application of injectable bone cements with enhanced biocompatibility. The crystal structure and chemical state of the synthesized PTCP and Si-HPMC as solid and liquid phase of the composite cements were measured by XRD and FT-IR. The handling and mechanical properties of cements were measured by injectability tests and threepoint bending tests. The in-vitro mechanical properties, XRD, and SEM results of bone cements were showed that enhanced hardening behavior was an inherent function of bone cements after in-vitro test. The cytotoxicity result of bone cements also was showed enhanced biocompatibility. Therefore, these injectable cements had potential be used as calcium phosphate cements for biomedical applications.

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