Carboxymethyl cellulose/polyethylene glycol superabsorbent hydrogel crosslinked with citric acid

DeukYong Lee (이득용); Cheolbyong Chun (전철병); Siwon Son (손시원); Yena Kim (김예나)

doi:10.6111/JKCGCT.2022.32.3.107

Carboxymethyl cellulose/polyethylene glycol superabsorbent hydrogel crosslinked with citric acid

Journal of the Korean Crystal Growth and Crystal Technology
Abbr : J. Korean Cryst. Growth Cryst. Technol.
2022, 32(3), pp.107-114
DOI : 10.6111/JKCGCT.2022.32.3.107
Publisher : The Korea Association Of Crystal Growth, Inc.
Research Area : Engineering > Materials Science and Engineering
Received : April 26, 2022
Accepted : May 23, 2022
Published : June 30, 2022

DeukYong Lee ¹, Cheolbyong Chun ¹, Siwon Son ¹, Yena Kim ¹

¹대림대학교

Accredited

ABSTRACT

Carboxymethyl cellulose/poly(ethylene glycol) (CMC/PEG) hydrogels crosslinked with citric acid (CA) are synthesized to evaluate the effect of CMC molecular weight (Mw), PEG and CA concentration on the optical property, swelling rate (SR), degradation rate (DR), and cytotoxicity and cell proliferation of hydrogels. For crosslinked CMC/PEG hydrogels, the FT-IR peak intensity associated with hydroxyl groups decreases due to PEG intercalation (esterification crosslinking) between CMC chains in a similar manner as the concentration of CA crosslinker increases. Crosslinked CMC (Mw = 90,000)/PEG hydrogels with 10 % CA dissolve regardless of PEG content. However, the SR of the CMC (Mw = 250,000)/PEG hydrogels decrease from 4923 % to 168 % with increasing PEG and CA concentrations from 0 to 20 % and from 0 to 25 %, respectively. As the Mw of CMC increases, the DR of the hydrogel is greatly improved. CMC (Mw = 250,000)/PEG10 hydrogels with 10 % CA exhibit the optimum properties of high absorbing capacity (3,200 %) with moderate DR (54 %), stiffness (1.39 ± 0.19 GPa), and cell viability (94.8 ± 1.3 %). CA-crosslinked CMC/PEG hydrogels are highly suitable for wound dressing or personal care applications due to their non-toxicity, good cell proliferation, SR, and mechanical properties.

KEYWORDS

Carboxymethyl cellulose (CMC), Polyethylene glycol, Citric acid, Crosslink, Superabsorbent hydrogel

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Journal of the Korean Crystal Growth and Crystal Technology 2023 KCI Impact Factor : 0.19

Carboxymethyl cellulose/polyethylene glycol superabsorbent hydrogel crosslinked with citric acid

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* References for papers published after 2023 are currently being built.

Journal of the Korean Crystal Growth and Crystal Technology 2023 KCI Impact Factor : 0.19

Carboxymethyl cellulose/polyethylene glycol superabsorbent hydrogel crosslinked with citric acid

ABSTRACT

KEYWORDS

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