@article{ART002303017},
author={Seon-Eun Baek and 백지윤 and Kang Ki Sung and Jeong-Eun Yoo},
title={Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2017},
volume={17},
number={2},
pages={111-118}
TY - JOUR
AU - Seon-Eun Baek
AU - 백지윤
AU - Kang Ki Sung
AU - Jeong-Eun Yoo
TI - Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency
JO - Journal of Korean Medicine for Obesity Research
PY - 2017
VL - 17
IS - 2
PB - The Society of Korean Medicine for Obesity Research
SP - 111
EP - 118
SN - 1976-9334
AB - Objectives: This study was conducted to evaluate the effects of Pueraria lobata (PL) extract onobesity related hormones in rats with estrogen deficiency.
Methods: The experiments were performed with the use of ovariectomized rats asestrogen-deficient obesity rat model. They were grouped Normal (sham operation group),Control (ovariectomy group), 50 mg/kg PL (ovariectomy group+50 mg/kg of PL), 100 mg/kg PL(ovariectomy group+100 mg/kg of PL), 200 mg/kg PL (ovariectomy group+200 mg/kg of PL).
PL extract was orally administered for 8 weeks once a day. Body weights and serum levels ofhormones, such as leptin, estradiol, cholecystokinin (CCK), ghrelin, and adiponectin wereestimated by ELISA.
Results: PL extract significantly decreased body weight, the serum levels of leptin inestrogen-deficient obesity rats. PL extract significantly increased the serum levels of estradioland CCK. However, PL extract did not directly effect on the levels of ghrelin and adiponectin inestrogen-deficient obesity rats.
Conclusions: It is concluded that PL extract reduced body weight, and regulate the hormonesrelated to energy metabolism. PL extract decreased the serum levels of leptin. PL extractincreased the serum levels of estradiol and CCK. These results indicate that PL might havepotentials for treatment of obesity and complications during the menopause caused byestrogen-deficiency.
Key Words: Obesity, Pueraria
KW - Obesity;Pueraria lobata;Menopause;Estrogens;Hormones
DO -
UR -
ER -
Seon-Eun Baek, 백지윤, Kang Ki Sung and Jeong-Eun Yoo. (2017). Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency. Journal of Korean Medicine for Obesity Research, 17(2), 111-118.
Seon-Eun Baek, 백지윤, Kang Ki Sung and Jeong-Eun Yoo. 2017, "Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency", Journal of Korean Medicine for Obesity Research, vol.17, no.2 pp.111-118.
Seon-Eun Baek, 백지윤, Kang Ki Sung, Jeong-Eun Yoo "Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency" Journal of Korean Medicine for Obesity Research 17.2 pp.111-118 (2017) : 111.
Seon-Eun Baek, 백지윤, Kang Ki Sung, Jeong-Eun Yoo. Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency. 2017; 17(2), 111-118.
Seon-Eun Baek, 백지윤, Kang Ki Sung and Jeong-Eun Yoo. "Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency" Journal of Korean Medicine for Obesity Research 17, no.2 (2017) : 111-118.
Seon-Eun Baek; 백지윤; Kang Ki Sung; Jeong-Eun Yoo. Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency. Journal of Korean Medicine for Obesity Research, 17(2), 111-118.
Seon-Eun Baek; 백지윤; Kang Ki Sung; Jeong-Eun Yoo. Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency. Journal of Korean Medicine for Obesity Research. 2017; 17(2) 111-118.
Seon-Eun Baek, 백지윤, Kang Ki Sung, Jeong-Eun Yoo. Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency. 2017; 17(2), 111-118.
Seon-Eun Baek, 백지윤, Kang Ki Sung and Jeong-Eun Yoo. "Effects of Pueraria lobata on Obesity Related Hormones in Rats with Estrogen Deficiency" Journal of Korean Medicine for Obesity Research 17, no.2 (2017) : 111-118.