Objectives: This study was conducted to evaluate efficacy and safety of Punica granatum L.ㆍActinidia chinensis Planch. mixed extract on body fat.
Methods: Thirty women were recruited (25 kg/m2≤body mass index [BMI]≤29.9 kg/m2) (19 yr≤age≤38 yr) and randomized to receive Punica granatum L.ㆍActinidia chinensis Planch. mixedextract or placebo for 8 weeks. During the test, they visited four times including screening. Bodyfat mass, body fat rate, anthropometric dimensions at waist and hip, waist-hip ratio, totalcholesterol, triglyceride, low density lipoprotein-cholesterol (LDL-C), and high densitylipoprotein-cholesterol (HDL-C) were measured at screening and 8 weeks after screening.
Adverse reaction were also checked each visit.
Results: There were no significant differences in all index. But when divide experimental group byBMI index, age, and compliance, less than BMI 27 kg/m2 group decreased body weight, body fatmass and more than BMI 27 kg/m2 group also decreased body weight, body fat mass and waistcircumference. Less than age 30 years group showed decline of waist circumference, fat free rateand T-cholesterol and more than age 30 years group showed decline of fat free mass. Group withcompliance more than 95% was decreased BMI, fat free mass, and hip circumference.
Conclusions: There was no significant efficacy as compared with placebo group, but as divideexperimental group according to BMI index, age, compliance, mixed extract might be effective toreduce obesity index.