@article{ART001219190},
author={홍성룡 and 손기락},
title={Constructing Gene Regulatory Networks using Knock-out Data},
journal={Journal of The Korea Society of Computer and Information},
issn={1598-849X},
year={2007},
volume={12},
number={6},
pages={105-114}
TY - JOUR
AU - 홍성룡
AU - 손기락
TI - Constructing Gene Regulatory Networks using Knock-out Data
JO - Journal of The Korea Society of Computer and Information
PY - 2007
VL - 12
IS - 6
PB - The Korean Society Of Computer And Information
SP - 105
EP - 114
SN - 1598-849X
AB - A gene regulatory network is a network of genes representing how genes influence the activities of other genes. Nowadays from microarray experiments, a large number of measurements on the expression levels of genes are available. One of typical data is the so-called "steady-state model" data measuring the expression levels of other genes after knocking out a particular gene. This paper shows how to reverse engineer a parsimonious gene regulatory network, using these measurement data. Our model considers auto-regulation, which forms a cycle in a genetic network. We also model repressor and enhancer roles of genes, which are not considered in previous known methods.
KW - Gene Regulatory Network;Directed Acyclic Graph
DO -
UR -
ER -
홍성룡 and 손기락. (2007). Constructing Gene Regulatory Networks using Knock-out Data. Journal of The Korea Society of Computer and Information, 12(6), 105-114.
홍성룡 and 손기락. 2007, "Constructing Gene Regulatory Networks using Knock-out Data", Journal of The Korea Society of Computer and Information, vol.12, no.6 pp.105-114.
홍성룡, 손기락 "Constructing Gene Regulatory Networks using Knock-out Data" Journal of The Korea Society of Computer and Information 12.6 pp.105-114 (2007) : 105.
홍성룡, 손기락. Constructing Gene Regulatory Networks using Knock-out Data. 2007; 12(6), 105-114.
홍성룡 and 손기락. "Constructing Gene Regulatory Networks using Knock-out Data" Journal of The Korea Society of Computer and Information 12, no.6 (2007) : 105-114.
홍성룡; 손기락. Constructing Gene Regulatory Networks using Knock-out Data. Journal of The Korea Society of Computer and Information, 12(6), 105-114.
홍성룡; 손기락. Constructing Gene Regulatory Networks using Knock-out Data. Journal of The Korea Society of Computer and Information. 2007; 12(6) 105-114.
홍성룡, 손기락. Constructing Gene Regulatory Networks using Knock-out Data. 2007; 12(6), 105-114.
홍성룡 and 손기락. "Constructing Gene Regulatory Networks using Knock-out Data" Journal of The Korea Society of Computer and Information 12, no.6 (2007) : 105-114.