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K-mer Based RNA-seq Read Distribution Method For Accelerating De Novo Transcriptome Assembly

  • Journal of The Korea Society of Computer and Information
  • Abbr : JKSCI
  • 2020, 25(8), pp.1-8
  • DOI : 10.9708/jksci.2020.25.08.001
  • Publisher : The Korean Society Of Computer And Information
  • Research Area : Engineering > Computer Science
  • Received : July 28, 2020
  • Accepted : August 13, 2020
  • Published : August 31, 2020

kwon hwi jun 1 Inuk Jung 1

1경북대학교

Accredited

ABSTRACT

In this paper, we propose a gene family based RNA-seq read distribution method in means to accelerate the overal transcriptome assembly computation time. To measure the performance of our transcriptome sequence data distribution method, we evaluated the performance by testing four types of data sets of the Arabidopsis thaliana genome (Whole Unclassified Reads, Family-Classified Reads, Model-Classified Reads, and Randomly Classified Reads). As a result of de novo transcript assembly in distributed nodes using model classification data, the generated gene contigs matched 95% compared to the contig generated by WUR, and the execution time was reduced by 4.2 times compared to a single node environment using the same resources.

Citation status

* References for papers published after 2023 are currently being built.

This paper was written with support from the National Research Foundation of Korea.