Objectives: The purpose of this study was to analyze the effects of health, diet, and oral health factors on frailty. Methods: The final study sample included 1,126 older adults aged 65 years or older using data from the 8th National Health and Nutrition Examination Survey (2019). All analyses were performed using SPSS (ver. 26.0) software, and statistical significance was set at p<0.05. Results: Frailty was higher in women, older adults, single individuals, those living alone, those with low household income and education levels, and those living in rural areas. Lack of regular walking, inadequate sleep duration, depressive experiences, underweight status, and diabetes were significantly associated with frailty. Food insecurity and a mean adequacy ratio of 0.75 or lower were associated with higher frailty levels. Total energy intake, as well as carbohydrate, protein, and fat intake, were lowest in the frail group. The analysis of factors affecting frailty showed that sex, age, economic activity, residential area, regular walking, depression, diabetes, mean adequacy ratio, dental examinations, and difficulty chewing were factors affecting frailty. Conclusions: By providing appropriate intervention programs for factors related to frailty, especially those that can be improved, frailty can be prevented, and healthy aging can be achieved.