Evaluation of saliva and cariogenic activity in patients with hematologic malignancy (혈액종양환자의 타액과 치아우식활성도 평가)

Kim, Hyeoungjoon (김형준); Kyung-Yi Chung (정경이); Park Ji il (박지일)

doi:10.13065/jksdh.2013.13.3.509

Evaluation of saliva and cariogenic activity in patients with hematologic malignancy

Journal of Korean society of Dental Hygiene
Abbr : J Korean Soc Dent Hyg
2013, 13(3), pp.509-515
DOI : 10.13065/jksdh.2013.13.3.509
Publisher : Korean Society of Dental Hygiene
Research Area : Medicine and Pharmacy > Dentistry

Kim, Hyeoungjoon ¹, Kyung-Yi Chung ², Park Ji il ³

¹전남대학교
²전남화순병원
³광주보건대학교

Accredited

ABSTRACT

Objectives : This study was performed to evaluate the salivary secretion, salivary pH and cariogenic activity using unstimulated whole saliva in patients with hematologic malignancy. Methods : Nineteen patients (9 male, 10 female) who had hematologic malignancy and were treated with chemotherapy or bone marrow transplantation, and nineteen normal volunteers (7male, 12 female) as control group were included. The mean age of patients group and control group was 45.1 and 46.7 years, respectively. Patients group was examined salivary secretion,salivary pH, and cariogenic activity using unstimulated whole saliva and was compared with control group. Results : In comparison with control group, salivary secretion, salivary pH and salivary buffer capacity were significantly lower in patients with hematologic malignancy (p<0.01). Both cariogenic activity(p<0.01) and the number of Lactobacilli(p<0.05) are higher in patients group than control group. Conclusions : These results suggest that the unstimulated whole salivary secretion, pH and buffer capacity were lower in patients with hematologic malignancy than control group. Cariogenic activity is higher in patients with hematologic malignancy than control group. Such salivary factor and cariogenic activity can increase the possibility of induction of dental caries.

KEYWORDS

cariogenic activity, hematologic malignancy, salivary pH, salivary secretion

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Journal of Korean society of Dental Hygiene 2023 KCI Impact Factor : 0.8

Evaluation of saliva and cariogenic activity in patients with hematologic malignancy

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Journal of Korean society of Dental Hygiene 2023 KCI Impact Factor : 0.8

Evaluation of saliva and cariogenic activity in patients with hematologic malignancy

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