@article{ART002240362},
author={choi byul bo ra and Kim， Ji-young and PARK SANG RYE},
title={Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells},
journal={Journal of Korean society of Dental Hygiene},
issn={2287-1705},
year={2017},
volume={17},
number={3},
pages={441-448},
doi={10.13065/jksdh.2017.17.03.441}
TY - JOUR
AU - choi byul bo ra
AU - Kim， Ji-young
AU - PARK SANG RYE
TI - Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells
JO - Journal of Korean society of Dental Hygiene
PY - 2017
VL - 17
IS - 3
PB - Korean Society of Dental Hygiene
SP - 441
EP - 448
SN - 2287-1705
AB - Objectives: The purpose of this study was to examine the cell proliferation and expression of alkaline phosphatase (ALP) during the differentiation of murine odontoblast-like cells (MDPC-23) by Cimicifuga rhizoma extract. Cimicifuga rhizoma extract was prepared using 70% ethanol. Then, the cells were treated with 25, 50, 100, 150, and 200 μg of Cimicifuga rhizoma extract. Methods: We determined the Cimicifuga rhizoma effects of MDPC-23 using WST-1 (water soluble tetrazolium salt-1) assay, ALP activity assay and histochemical staining. Results: 25-200 μg of Cimicifuga rhizoma extract did not inhibit the growth of MDPC-23 cells; 100±0, 100±3.29, 99±4.86, 98±3.80, 98±1.73, 99±5.05% (p<0.794). 50 μg of Cimicifuga rhizoma extract stimulated ALP activity on MDPC-23; 5.1±0.20 units/μℓ (p<0.001). Conclusions: It was proven that Cimicifuga rhizoma promoted differentiation of MDPC- 23 cells.
KW - Alkaline phosphatase;Cimicifuga rhizoma;Differentiation;Odontoblast
DO - 10.13065/jksdh.2017.17.03.441
ER -
choi byul bo ra, Kim， Ji-young and PARK SANG RYE. (2017). Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells. Journal of Korean society of Dental Hygiene, 17(3), 441-448.
choi byul bo ra, Kim， Ji-young and PARK SANG RYE. 2017, "Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells", Journal of Korean society of Dental Hygiene, vol.17, no.3 pp.441-448. Available from: doi:10.13065/jksdh.2017.17.03.441
choi byul bo ra, Kim， Ji-young, PARK SANG RYE "Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells" Journal of Korean society of Dental Hygiene 17.3 pp.441-448 (2017) : 441.
choi byul bo ra, Kim， Ji-young, PARK SANG RYE. Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells. 2017; 17(3), 441-448. Available from: doi:10.13065/jksdh.2017.17.03.441
choi byul bo ra, Kim， Ji-young and PARK SANG RYE. "Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells" Journal of Korean society of Dental Hygiene 17, no.3 (2017) : 441-448.doi: 10.13065/jksdh.2017.17.03.441
choi byul bo ra; Kim， Ji-young; PARK SANG RYE. Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells. Journal of Korean society of Dental Hygiene, 17(3), 441-448. doi: 10.13065/jksdh.2017.17.03.441
choi byul bo ra; Kim， Ji-young; PARK SANG RYE. Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells. Journal of Korean society of Dental Hygiene. 2017; 17(3) 441-448. doi: 10.13065/jksdh.2017.17.03.441
choi byul bo ra, Kim， Ji-young, PARK SANG RYE. Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells. 2017; 17(3), 441-448. Available from: doi:10.13065/jksdh.2017.17.03.441
choi byul bo ra, Kim， Ji-young and PARK SANG RYE. "Effect of Cimicifuga rhizoma extract on the odontoblastic differentiation of MDPC-23 cells" Journal of Korean society of Dental Hygiene 17, no.3 (2017) : 441-448.doi: 10.13065/jksdh.2017.17.03.441
1,
Kim， Ji-young
2,
PARK SANG RYE
2
