2020, Vol.33, No.3

Assessment of Histomorphological Features of Tibia and Fibula for Age Estimation in Koreans

Lataelok , Kim， Deog Im , KIM YISUK | 2020, 33(3) | pp.107~115 | number of Cited : 0

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Estimation of age at death is one of the first and most important step with sex determination and stature estimation for individual identification in physical and forensic anthropologies. Recently, histomorphological methods have attempted to estimate age at death through the osteon. In particular, it is known that the long bones are less affected by external factors and are frequently found in a complete form, and the accuracy of age estimation is also high. The purpose of this study is to help estimate age of skeletal remains, which is found by developing equations to estimate age at death using the tibia and fibula extracted from the Korean cadavers. The right tibias and fibulas of 31 Korean cadavers were extracted in anatomy dissection at medical school, and then produced and photographed bone tissue slices. Number of intact osteon (Pi) and number of fragmentary osteon (Pf), osteon population density (OPD), average osteon area (OA), relative cortical area (RCA), cortical width (CW) of each sample was measured and statistically analyzed. Seven of all measurements of the tibia and fibula had statistically significant difference between sexes (p<0.05). Pi of the tibia in male and Pf, OPD, RCA of the fibula in female were statistically correlated with age. In simple regression analysis, RCA of the fibula in female had highest regression coefficient (0.62) and its standard error estimate (SEE) was 8 years. Equation at multiple regression analysis which was the tibia and fibula in male had 0.44 (R-squared value) and 11years (SEE). In female, regression coefficient was 0.91, SEE was 6 years. In this study, the results in female were higher than in male and in others. This study was the first attempt to estimate age at death and was proved the possibility of estimating age using the tibia and fibula in Korean. As a result of this study, it was found that equations suitable for sex and population-specific were needed to estimate the accurate age, using the tibia and fibula of skeletal remains in Koreans could help estimate age at death with high accuracy.

Anatomical Characteristics of the Calcaneofibular Ligament of Ankle Joint in Korean Population

Hyung Wook Kwon

, Cho Jae Ho

, Digud Kim

and 5 other persons | 2020, 33(3) | pp.117~123 | number of Cited : 0

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Magnesium Hydride Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia

Myeong Jin Lee , Ji Hye Lee , Do Kyung Kim and 6 other persons | 2020, 33(3) | pp.125~134 | number of Cited : 0

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Reactive oxygen species (ROS)-mediated oxidative stress plays a key role in the pathogenesis of central nervous system diseases, including vascular dementia (VaD). Thus, scientific attention has been given to the uptake of molecular hydrogen (H2), a powerful ROS scavenger that is abundant in nature, as a potential therapeutic candidate. Among the methods to supply H2, we selected an oral supplement of magnesium hydride (MgH2) and investigated its therapeutic role in cognitive impairment and hippocampal neuronal death associated with VaD. Sprague Dawley rats were randomly divided into 4 groups (n of each=8) and subjected to different conditions: SO, a group with vehicle and sham-operation; VEH, a group with a vehicle and 2VO/H (2 vessel occlusion and hypovolemia, used as a surgical model of VaD); MH-L, a group with low dose (5 mg/kg) of MgH2 and 2VO/H; and MH-H, a group with high dose (15 mg/kg) of MgH2 and 2VO/H. MgH2 or vehicle was administered via an intragastric route for 14 days before the operation. Subsequently, the memory performances of rats were tested using three behavior tests, i.e., Y-maze-, Barnes maze-, and passive avoidance tests (PAT). On postoperative day 8, the number of viable neurons in the hippocampal Cornu Ammonis (CA) 1 region was measured. The results of behavioral tests revealed that memory performance was significantly hampered in the VEH group when compared with the SO group; however, the extent of the impairment was markedly diminished in the MH-L and MH-H groups. While the number of pyramidal neurons in hippocampal CA1 was largely reduced in the VEH group when compared with the SO group, this reduction was significantly attenuated in the MH-L and MH-H groups. The effects of MgH2 were dose-dependent in PAT and histologic experiments. These results suggest that MgH2 supplementation can attenuate cognitive impairment and hippocampal neuronal death associated with VaD.

The Visible Korean: Movable Surface Models of the Foot

김슬기 , Chung Yoh Kim , Jin Seo Park | 2020, 33(3) | pp.135~142 | number of Cited : 1

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Complex Variations of Plantaris Muscle Origin, Course and Insertion: A Cadaveric Case Report

Park Kwang Rak , Cho Jae Ho , Yu Jin Choi and 5 other persons | 2020, 33(3) | pp.143~147 | number of Cited : 2

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Retraction: Protective Effect of Magnolol Against Ceramide-induced Apoptosis in SK-N-SH cells

Lee DY , Kim SS , Kim KY and 1 other persons | 2020, 33(3) | pp.149~149 | number of Cited : 0

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Retraction: Attenuated Ceramide-induced Neuronal Apoptosis by Acanthopanax senticous

Lee DY , Kim DS , Sohn DS and 3 other persons | 2020, 33(3) | pp.150~150 | number of Cited : 0

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Retraction: Studies on Signal Transduction Mechanism of Alcohol-induced Neuronal Cell Death and Protective Effect

Lee DY , Kim SS , Kyung-Yong Kim and 5 other persons | 2020, 33(3) | pp.151~151 | number of Cited : 0

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Retraction: Down-regulated Reactive Oxygen Species by Heat Shock Protein 90 in 3-Hydroxykynurenine-induced SKN-SH Cell Death

Kim DS , Lee MW , Noh YH and 8 other persons | 2020, 33(3) | pp.152~152 | number of Cited : 0

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Retraction: BF-7 Improved Memory Function and Protected Neuron from Oxidative Stress

Lee MY , Lee SH , Lee JS and 11 other persons | 2020, 33(3) | pp.153~153 | number of Cited : 0

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Retraction: Study on the Mitochondrial Dysfunction by p53 Regulation in Ceramide-induced Neuronal Cell Death

Lee DY , Lee HJ , Noh YH and 6 other persons | 2020, 33(3) | pp.154~154 | number of Cited : 0

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Retraction: Protective Effect of HSP90 on Neuronal Cell Death-induced by beta-Amyloid Peptide

Lee HJ , Kim DH , Kim OH and 4 other persons | 2020, 33(3) | pp.155~155 | number of Cited : 0

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Journal Central

Anatomy & Biological Anthropology 2023 KCI Impact Factor : 0.33

2020, Vol.33, No.3