@article{ART001144106},
author={윤상필 and 전제열 and Yong Lim and 김인정 and 김주영 and 김장만 and Inyoub Jang},
title={Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2004},
volume={17},
number={3},
pages={207-214},
doi={10.11637/aba.2004.17.3.207}
TY - JOUR
AU - 윤상필
AU - 전제열
AU - Yong Lim
AU - 김인정
AU - 김주영
AU - 김장만
AU - Inyoub Jang
TI - Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell
JO - Anatomy & Biological Anthropology
PY - 2004
VL - 17
IS - 3
PB - 대한체질인류학회
SP - 207
EP - 214
SN - 2671-5651
AB - In addition to the central and the peripheral nervous system, calcitonin gene-related peptide-like immunoreactivity
(CGRP-LI) has been identified throughout the enteric nervous system. Several functions of the CGRP in
gastrointestinal (G-I) tract has been identified, but the effect of CGRP on G-I motility is unclear. The distribution of
calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in the murine small bowel were studied by using
immunohistochemistry, also analyzed functionally by using electrophysiological method. Immunohistochemical studies
demonstrated that CGRP-LI is localized in both nerve fibers and myenteric ganglion cells in the whole-mount
preparation of murine small intestine. Double labelling with CGRP and c-kit investigated by confocal microscope was
shown that CGRP-LI enteric nerve fiber surrounded the c-kit positive interstitial cells of Cajal (ICC). Electrophysiological
finding revealed that treatment of CGRP inhibited electrical activity on culture ICC. Our results suggest a CGRP
innervation of murine small bowel ICC. The released CGRP from enteric nerve terminals may induce relaxation of
small bowel through the inhibition of ICC.
KW - Calcitonin gene-related peptide(CGRP);Enteric muscle;Bowel motility;Mouse
DO - 10.11637/aba.2004.17.3.207
ER -
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만 and Inyoub Jang. (2004). Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell. Anatomy & Biological Anthropology, 17(3), 207-214.
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만 and Inyoub Jang. 2004, "Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell", Anatomy & Biological Anthropology, vol.17, no.3 pp.207-214. Available from: doi:10.11637/aba.2004.17.3.207
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만, Inyoub Jang "Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell" Anatomy & Biological Anthropology 17.3 pp.207-214 (2004) : 207.
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만, Inyoub Jang. Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell. 2004; 17(3), 207-214. Available from: doi:10.11637/aba.2004.17.3.207
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만 and Inyoub Jang. "Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell" Anatomy & Biological Anthropology 17, no.3 (2004) : 207-214.doi: 10.11637/aba.2004.17.3.207
윤상필; 전제열; Yong Lim; 김인정; 김주영; 김장만; Inyoub Jang. Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell. Anatomy & Biological Anthropology, 17(3), 207-214. doi: 10.11637/aba.2004.17.3.207
윤상필; 전제열; Yong Lim; 김인정; 김주영; 김장만; Inyoub Jang. Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell. Anatomy & Biological Anthropology. 2004; 17(3) 207-214. doi: 10.11637/aba.2004.17.3.207
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만, Inyoub Jang. Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell. 2004; 17(3), 207-214. Available from: doi:10.11637/aba.2004.17.3.207
윤상필, 전제열, Yong Lim, 김인정, 김주영, 김장만 and Inyoub Jang. "Calcotonin gene-related peptide immunoreactivity in the muscle layer of small intestine; its action on interstitial cell" Anatomy & Biological Anthropology 17, no.3 (2004) : 207-214.doi: 10.11637/aba.2004.17.3.207