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@article{ART001211494},
author={Lee Won-Jeong and 손성경 and 이민아 and 양윤석 and 김원식},
title={Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2007},
volume={20},
number={3},
pages={201-211},
doi={10.11637/aba.2007.20.3.201}

TY - JOUR
AU - Lee Won-Jeong
AU - 손성경
AU - 이민아
AU - 양윤석
AU - 김원식
TI - Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle
JO - Anatomy & Biological Anthropology
PY - 2007
VL - 20
IS - 3
PB - 대한체질인류학회
SP - 201
EP - 211
SN - 2671-5651
AB - Hormesis is the generally-favorable biological responses to low exposures to toxins and other stressors. Radiation hormesis is the theory that ionizing radiation is benign at low levels of exposure, and that doses at the level of natural background radiation can be beneficial. The purpose of this study is to reveal the hormetic effect of low-dose radiation of ionizing radiation on the ovarian follicles of 4-week old female mice. Mice were grouped into control group, 2 cGy irradiated group, 2 cGy and 2 Gy irradiated group (2 cGY pre-exposure group), and 2 Gy irradited group. Mice were sacrificed by cervical dislocation 24 hours after irradiation, removed ovaries, fixed in neutral formaldehyde solution for 24 hours, embedded with paraffin, stained with hematoxylin and eosin and TUNEL immunohistochemically, and observed light microscopically the atretic follicles and normal follicles in various follicular developmental stages. In this experiment, the ratrio of atretic follicles to entire follicles in an ovary increased significantly in 2 Gyirradiated group compared with 2 cGY pre-exposure group, and the ratio of normal follicles to the entire follicles in an ovary in all the developmental stages were increased significantly in the 2 cGY pre-exposure group compared with 2 Gy-irradiated group. These results mean that low-dose radiation pre-exposure can induce the hormetic effect in the developing ovarian follicle.
KW - Hormesis;Follicular atresia;Apotosis;TUNEL
DO - 10.11637/aba.2007.20.3.201
ER -

Lee Won-Jeong, 손성경, 이민아, 양윤석 and 김원식. (2007). Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle. Anatomy & Biological Anthropology, 20(3), 201-211.

Lee Won-Jeong, 손성경, 이민아, 양윤석 and 김원식. 2007, "Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle", Anatomy & Biological Anthropology, vol.20, no.3 pp.201-211. Available from: doi:10.11637/aba.2007.20.3.201

Lee Won-Jeong, 손성경, 이민아, 양윤석, 김원식 "Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle" Anatomy & Biological Anthropology 20.3 pp.201-211 (2007) : 201.

Lee Won-Jeong, 손성경, 이민아, 양윤석, 김원식. Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle. 2007; 20(3), 201-211. Available from: doi:10.11637/aba.2007.20.3.201

Lee Won-Jeong, 손성경, 이민아, 양윤석 and 김원식. "Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle" Anatomy & Biological Anthropology 20, no.3 (2007) : 201-211.doi: 10.11637/aba.2007.20.3.201

Lee Won-Jeong; 손성경; 이민아; 양윤석; 김원식. Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle. Anatomy & Biological Anthropology, 20(3), 201-211. doi: 10.11637/aba.2007.20.3.201

Lee Won-Jeong; 손성경; 이민아; 양윤석; 김원식. Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle. Anatomy & Biological Anthropology. 2007; 20(3) 201-211. doi: 10.11637/aba.2007.20.3.201

Lee Won-Jeong, 손성경, 이민아, 양윤석, 김원식. Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle. 2007; 20(3), 201-211. Available from: doi:10.11637/aba.2007.20.3.201

Lee Won-Jeong, 손성경, 이민아, 양윤석 and 김원식. "Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle" Anatomy & Biological Anthropology 20, no.3 (2007) : 201-211.doi: 10.11637/aba.2007.20.3.201