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@article{ART001228658},
author={송인환 and 김성용},
title={Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2007},
volume={20},
number={4},
pages={311-320},
doi={10.11637/aba.2007.20.4.311}

TY - JOUR
AU - 송인환
AU - 김성용
TI - Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture
JO - Anatomy & Biological Anthropology
PY - 2007
VL - 20
IS - 4
PB - 대한체질인류학회
SP - 311
EP - 320
SN - 2671-5651
AB - Homeostasis of the body is maintained by balance of cell renewal, differentiation, and death. Dexamethasone has been used long time in field of MSCs research as differentiation inducer while, in contrast, there has been little work on the effect of dexamethasone on apoptosis and proliferation of MSCs. To determine the effect of dexamethasone on apoptosis and proliferation, MSCs were cultivated with (Dex) or without (Con) dexamethasone for 3 weeks. During this period weekly cell count, DNA assay, mitosis, apoptosis as well as alkaline phosphatase assay observation were recorded. DNA and cell number of Dex group was lower than Con group in early period but exceed at 3th week. There is no significant difference in mitosis between both groups whereas apoptosis frequency in Dex group was lower than that of in Con group. These results indicate that dexamethasone influences cell proliferation of MSCs in long term confluent culture by suppression of apoptosis.
KW - Mesenchymal stem cells;Dexamethasone;Proliferation;Apoptosis
DO - 10.11637/aba.2007.20.4.311
ER -

송인환 and 김성용. (2007). Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture. Anatomy & Biological Anthropology, 20(4), 311-320.

송인환 and 김성용. 2007, "Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture", Anatomy & Biological Anthropology, vol.20, no.4 pp.311-320. Available from: doi:10.11637/aba.2007.20.4.311

송인환, 김성용 "Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture" Anatomy & Biological Anthropology 20.4 pp.311-320 (2007) : 311.

송인환, 김성용. Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture. 2007; 20(4), 311-320. Available from: doi:10.11637/aba.2007.20.4.311

송인환 and 김성용. "Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture" Anatomy & Biological Anthropology 20, no.4 (2007) : 311-320.doi: 10.11637/aba.2007.20.4.311

송인환; 김성용. Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture. Anatomy & Biological Anthropology, 20(4), 311-320. doi: 10.11637/aba.2007.20.4.311

송인환; 김성용. Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture. Anatomy & Biological Anthropology. 2007; 20(4) 311-320. doi: 10.11637/aba.2007.20.4.311

송인환, 김성용. Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture. 2007; 20(4), 311-320. Available from: doi:10.11637/aba.2007.20.4.311

송인환 and 김성용. "Effects of Dexamethasone on Proliferationof Mesenchymal Stem Cells in Long Term Culture" Anatomy & Biological Anthropology 20, no.4 (2007) : 311-320.doi: 10.11637/aba.2007.20.4.311