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@article{ART001380195},
author={강지혜 and Hyeonjin Kim and 정지연 and 김민석 and Won-Jae Kim and 이은주 and 김선헌 and 정준용 and 고현미},
title={Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2009},
volume={22},
number={3},
pages={235-244},
doi={10.11637/aba.2009.22.3.235}

TY - JOUR
AU - 강지혜
AU - Hyeonjin Kim
AU - 정지연
AU - 김민석
AU - Won-Jae Kim
AU - 이은주
AU - 김선헌
AU - 정준용
AU - 고현미
TI - Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development
JO - Anatomy & Biological Anthropology
PY - 2009
VL - 22
IS - 3
PB - 대한체질인류학회
SP - 235
EP - 244
SN - 2671-5651
AB - Understanding the genetic control of tooth eruption is one of the major issues in tooth development. Thus far, it is known that eruption-related molecules are secreted from follicular cells surrounding the germs and are related mainly to osteoclast formation. This study examined the involvement of CD147 and its downstream molecules in the eruption of rat developing molars using immunohistochemistry, RT-PCR and histomorphometry. CD147 was expressed differentially in the cap (3rd molar germs) and root formation (2nd molar germs) stages in tooth development. CD147 was localized immunohistochemically in the follicular cells and osteoclasts as well as in the ameloblasts and odontoblasts. The expression pattern of CD147 and mmps was investigated because CD147 is an mmp inducer. The expression of both mmp-2 and -9 increased at the root formation stage compared to that at the cap stage and increased in a stage dependent manner. However, the level of mmp-13 was not changed notably. The histomorphometrical study suggested that the number of osteoclasts that appeared occlusal to the molar germs for the resorption of alveolar bone increased significantly during development. These results suggest that CD147 may play an important role in the formation of the eruption pathway along with the mmps.
KW - CD147;Tooth eruption;mmps
DO - 10.11637/aba.2009.22.3.235
ER -

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용 and 고현미. (2009). Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development. Anatomy & Biological Anthropology, 22(3), 235-244.

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용 and 고현미. 2009, "Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development", Anatomy & Biological Anthropology, vol.22, no.3 pp.235-244. Available from: doi:10.11637/aba.2009.22.3.235

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용, 고현미 "Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development" Anatomy & Biological Anthropology 22.3 pp.235-244 (2009) : 235.

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용, 고현미. Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development. 2009; 22(3), 235-244. Available from: doi:10.11637/aba.2009.22.3.235

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용 and 고현미. "Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development" Anatomy & Biological Anthropology 22, no.3 (2009) : 235-244.doi: 10.11637/aba.2009.22.3.235

강지혜; Hyeonjin Kim; 정지연; 김민석; Won-Jae Kim; 이은주; 김선헌; 정준용; 고현미. Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development. Anatomy & Biological Anthropology, 22(3), 235-244. doi: 10.11637/aba.2009.22.3.235

강지혜; Hyeonjin Kim; 정지연; 김민석; Won-Jae Kim; 이은주; 김선헌; 정준용; 고현미. Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development. Anatomy & Biological Anthropology. 2009; 22(3) 235-244. doi: 10.11637/aba.2009.22.3.235

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용, 고현미. Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development. 2009; 22(3), 235-244. Available from: doi:10.11637/aba.2009.22.3.235

강지혜, Hyeonjin Kim, 정지연, 김민석, Won-Jae Kim, 이은주, 김선헌, 정준용 and 고현미. "Feasibility of CD147 for an Eruption-Related Molecule during Rat Molar Development" Anatomy & Biological Anthropology 22, no.3 (2009) : 235-244.doi: 10.11637/aba.2009.22.3.235