@article{ART002942080},
author={Su-Youn Lee and Ki Hwan Han},
title={Response of Renal Intercalated Cells to Dietary Potassium Intake},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2023},
volume={36},
number={1},
pages={1-7},
doi={10.11637/aba.2023.36.1.1}
TY - JOUR
AU - Su-Youn Lee
AU - Ki Hwan Han
TI - Response of Renal Intercalated Cells to Dietary Potassium Intake
JO - Anatomy & Biological Anthropology
PY - 2023
VL - 36
IS - 1
PB - 대한체질인류학회
SP - 1
EP - 7
SN - 2671-5651
AB - While ancient humans consumed enough potassium (K+), modern humans have insufficient K+ intake. The renal collecting duct plays an important role in regulating K+ homeostasis. There are at least three different types of cells in the collecting duct. The purpose of this study is to examine the effects of dietary K+ intake on collecting duct intercalated cells. C57BL/6 mice had free access to a control (1%), low (<0.01%), or high (5%) K+ diet for 1 week. Kidney tissue were processed for light microscopic immunohistochemistry and image analysis. Excessive dietary K+ intake or deficiency significantly changed blood K+ concentrations in mice. The size of type A intercalated cells increased by about 1.6 times in the low K+ group and decreased in the high K+ group. Conversely, the size of type B intercalated cells decreased in the low K+ group and increased in the high K+ group. The response of NANB cells to dietary K+ intake was generally like type B cells. These results demonstrated that renal intercalated cells vary greatly with dietary K+ intake. The structural changes in response to K+ imbalance may be closely related to cardiovascular and renal disorders in modern humans.
KW - Kidney;Collecting duct;Potassium;Modern human
DO - 10.11637/aba.2023.36.1.1
ER -
Su-Youn Lee and Ki Hwan Han. (2023). Response of Renal Intercalated Cells to Dietary Potassium Intake. Anatomy & Biological Anthropology, 36(1), 1-7.
Su-Youn Lee and Ki Hwan Han. 2023, "Response of Renal Intercalated Cells to Dietary Potassium Intake", Anatomy & Biological Anthropology, vol.36, no.1 pp.1-7. Available from: doi:10.11637/aba.2023.36.1.1
Su-Youn Lee, Ki Hwan Han "Response of Renal Intercalated Cells to Dietary Potassium Intake" Anatomy & Biological Anthropology 36.1 pp.1-7 (2023) : 1.
Su-Youn Lee, Ki Hwan Han. Response of Renal Intercalated Cells to Dietary Potassium Intake. 2023; 36(1), 1-7. Available from: doi:10.11637/aba.2023.36.1.1
Su-Youn Lee and Ki Hwan Han. "Response of Renal Intercalated Cells to Dietary Potassium Intake" Anatomy & Biological Anthropology 36, no.1 (2023) : 1-7.doi: 10.11637/aba.2023.36.1.1
Su-Youn Lee; Ki Hwan Han. Response of Renal Intercalated Cells to Dietary Potassium Intake. Anatomy & Biological Anthropology, 36(1), 1-7. doi: 10.11637/aba.2023.36.1.1
Su-Youn Lee; Ki Hwan Han. Response of Renal Intercalated Cells to Dietary Potassium Intake. Anatomy & Biological Anthropology. 2023; 36(1) 1-7. doi: 10.11637/aba.2023.36.1.1
Su-Youn Lee, Ki Hwan Han. Response of Renal Intercalated Cells to Dietary Potassium Intake. 2023; 36(1), 1-7. Available from: doi:10.11637/aba.2023.36.1.1
Su-Youn Lee and Ki Hwan Han. "Response of Renal Intercalated Cells to Dietary Potassium Intake" Anatomy & Biological Anthropology 36, no.1 (2023) : 1-7.doi: 10.11637/aba.2023.36.1.1