@article{ART003154961},
author={지미진 and 뭉궁치메그 and 송수진 and 이수연 and 박소현 and Jung Mi Han and Ki Hwan Han},
title={A comparative study of primary cilia length in renal tubules using scanning electron microscopy},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2024},
volume={37},
number={4},
pages={279-286},
doi={10.11637/aba.2024.37.4.279}
TY - JOUR
AU - 지미진
AU - 뭉궁치메그
AU - 송수진
AU - 이수연
AU - 박소현
AU - Jung Mi Han
AU - Ki Hwan Han
TI - A comparative study of primary cilia length in renal tubules using scanning electron microscopy
JO - Anatomy & Biological Anthropology
PY - 2024
VL - 37
IS - 4
PB - 대한체질인류학회
SP - 279
EP - 286
SN - 2671-5651
AB - The primary cilium is a hair-like structure extending from the luminal surface of kidney tubular cells. Its microstructure and function in the kidney are still not fully understood. This study aimed to detect and compare primary cilia across various renal tubules. Normal adult Sprague-Dawley rats were perfused with 2% periodate-lysine-paraformaldehyde fixative and processed for light and electron microscopy. Antibodies against acetylated α-tubulin and aquaporin 1 were used to label primary cilia and proximal tubules, respectively. Primary cilia were largely concealed among the microvilli in proximal tubules, making accurate observation challenging under electron microscopy. No significant differences were found in the lengths of primary cilia in the distal tubules (2.1 ± 0.22 μm) and collecting ducts (1.86 ± 0.31 μm). However, primary cilia in the thin limbs of the loop of Henle were significantly longer, measuring 4.2 ± 0.73 μm, compared to those in adjacent distal tubules and collecting ducts. These findings demonstrate that the primary cilia in the thin limbs are the longest in the normal kidney, suggesting they may have a distinct function in this segment.
KW - Primary cilia;Renal tubules;Thin limbs;Electron microscopy
DO - 10.11637/aba.2024.37.4.279
ER -
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han and Ki Hwan Han. (2024). A comparative study of primary cilia length in renal tubules using scanning electron microscopy. Anatomy & Biological Anthropology, 37(4), 279-286.
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han and Ki Hwan Han. 2024, "A comparative study of primary cilia length in renal tubules using scanning electron microscopy", Anatomy & Biological Anthropology, vol.37, no.4 pp.279-286. Available from: doi:10.11637/aba.2024.37.4.279
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han, Ki Hwan Han "A comparative study of primary cilia length in renal tubules using scanning electron microscopy" Anatomy & Biological Anthropology 37.4 pp.279-286 (2024) : 279.
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han, Ki Hwan Han. A comparative study of primary cilia length in renal tubules using scanning electron microscopy. 2024; 37(4), 279-286. Available from: doi:10.11637/aba.2024.37.4.279
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han and Ki Hwan Han. "A comparative study of primary cilia length in renal tubules using scanning electron microscopy" Anatomy & Biological Anthropology 37, no.4 (2024) : 279-286.doi: 10.11637/aba.2024.37.4.279
지미진; 뭉궁치메그; 송수진; 이수연; 박소현; Jung Mi Han; Ki Hwan Han. A comparative study of primary cilia length in renal tubules using scanning electron microscopy. Anatomy & Biological Anthropology, 37(4), 279-286. doi: 10.11637/aba.2024.37.4.279
지미진; 뭉궁치메그; 송수진; 이수연; 박소현; Jung Mi Han; Ki Hwan Han. A comparative study of primary cilia length in renal tubules using scanning electron microscopy. Anatomy & Biological Anthropology. 2024; 37(4) 279-286. doi: 10.11637/aba.2024.37.4.279
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han, Ki Hwan Han. A comparative study of primary cilia length in renal tubules using scanning electron microscopy. 2024; 37(4), 279-286. Available from: doi:10.11637/aba.2024.37.4.279
지미진, 뭉궁치메그, 송수진, 이수연, 박소현, Jung Mi Han and Ki Hwan Han. "A comparative study of primary cilia length in renal tubules using scanning electron microscopy" Anatomy & Biological Anthropology 37, no.4 (2024) : 279-286.doi: 10.11637/aba.2024.37.4.279