@article{ART001231056},
author={Chung Yoon Hee and 안향선},
title={Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2008},
volume={21},
number={1},
pages={69-75},
doi={10.11637/aba.2008.21.1.69}
TY - JOUR
AU - Chung Yoon Hee
AU - 안향선
TI - Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum
JO - Anatomy & Biological Anthropology
PY - 2008
VL - 21
IS - 1
PB - 대한체질인류학회
SP - 69
EP - 75
SN - 2671-5651
AB - Channels formed by the transient receptor potential (TRP) family of proteins have a variety of physiological
functions. In the present study, we examined the localization of canonical transient receptor potential channels (TRPCs)
in rat cerebellum.
Twelve adult (4~6 month old) Sprague-Dawley rats were examined in this study. We performed immunohistochemistry
using specific antibodies against TRPCs to investigate the detailed and comparative distribution of six TRPCs in
rat cerebellum.
There was a high density of TRPC1, TRPC3, TRPC4, TRPC5 and TRPC7, with a much lower density of TRPC6 in
the rat cerebellar cortex. The somatodendritic Purkinje cell areas were intensely stained with antiTRPC3, TRPC4, TRPC5
or TRPC7 antibodies, whereas the staining intensity of TRPC6 was relatively low in the Purkinje cell bodies. In
the cerebellar nuclei, the cell bodies of cerebellar output neurons showed moderate TRPC1, TRPC3, TRPC5 and TRPC7
immunoreactivities, while TRPC6 immunoreactivity was observed in the surrounding neuropil.
This study showing the differential localizations of TRPC channels in the cerebellum may provide useful data for the
future investigations on the structural and functional properties of TRPCs.
KW - Transient receptor potential (TRP) channels;TRPC;Rat;Cerebellum;Immunohistochemistry
DO - 10.11637/aba.2008.21.1.69
ER -
Chung Yoon Hee and 안향선. (2008). Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum. Anatomy & Biological Anthropology, 21(1), 69-75.
Chung Yoon Hee and 안향선. 2008, "Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum", Anatomy & Biological Anthropology, vol.21, no.1 pp.69-75. Available from: doi:10.11637/aba.2008.21.1.69
Chung Yoon Hee, 안향선 "Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum" Anatomy & Biological Anthropology 21.1 pp.69-75 (2008) : 69.
Chung Yoon Hee, 안향선. Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum. 2008; 21(1), 69-75. Available from: doi:10.11637/aba.2008.21.1.69
Chung Yoon Hee and 안향선. "Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum" Anatomy & Biological Anthropology 21, no.1 (2008) : 69-75.doi: 10.11637/aba.2008.21.1.69
Chung Yoon Hee; 안향선. Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum. Anatomy & Biological Anthropology, 21(1), 69-75. doi: 10.11637/aba.2008.21.1.69
Chung Yoon Hee; 안향선. Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum. Anatomy & Biological Anthropology. 2008; 21(1) 69-75. doi: 10.11637/aba.2008.21.1.69
Chung Yoon Hee, 안향선. Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum. 2008; 21(1), 69-75. Available from: doi:10.11637/aba.2008.21.1.69
Chung Yoon Hee and 안향선. "Immunohistochemical Study on the Distributionof Canonical Transient Receptor Potential Channelsin Rat Cerebellum" Anatomy & Biological Anthropology 21, no.1 (2008) : 69-75.doi: 10.11637/aba.2008.21.1.69
