This study explored stigma effects on people with gaming disorder when gaming disorder is included to ICD-11(International Classification Diseases-11). Using general samples, the roles of self-esteem, self-efficacy, and cultural dimensions on stigma perceptions are investigated. The findings of this study showed that female and older people reacted more sensitively on stigma perceptions. Self-esteem is negatively related to Impossibility to recover and Incompetence. For cultural orientation, power distance and masculinity positively influenced dangerousness and impossibility to recover. Distinguishability and incompetence are influenced by power distance, masculinity, and collectivism. People who agree to the inclusion of gaming disorder to ICD-11 positively perceived dangerousness, distinguishability, and incompetence. Relationship with impossibility to recover showed limited significance. These results could provide implications that inclusion of gaming disorder to ICD-11 could evoke stigma effects on people with gaming disorder.