@article{ART003263304},
author={Yun Seo Shim and Eun Ji Choi and Ja Hyun Lee},
title={Drug Delivery Systems(DDS): Focusing on Disease Application Cases},
journal={Industry Promotion Research},
issn={2466-1139},
year={2025},
volume={10},
number={4},
pages={179-189},
doi={10.21186/IPR.2025.10.4.179}
TY - JOUR
AU - Yun Seo Shim
AU - Eun Ji Choi
AU - Ja Hyun Lee
TI - Drug Delivery Systems(DDS): Focusing on Disease Application Cases
JO - Industry Promotion Research
PY - 2025
VL - 10
IS - 4
PB - Industrial Promotion Institute
SP - 179
EP - 189
SN - 2466-1139
AB - This paper reviews recent advances and challenges in Drug Delivery Systems (DDS) as an essential strategy to enhance the therapeutic efficiency of conventional drugs. DDS aims to improve the stability, targeting ability, and controlled release profiles of drugs using various carriers such as polymeric nanoparticles, lipid nanoparticles (LNPs), and hydrogels. The paper discusses the classification of DDS by release mechanisms (immediate, sustained, stimuli-responsive), delivery routes (oral, transdermal, injection, mucosal, pulmonary, direct local delivery), and carrier types. It highlights practical applications in cancer therapy, chronic disease management, vaccine delivery, and treatment of neurological disorders. Representative case studies and experimental data demonstrate the superior therapeutic effects of DDS compared to free drugs. Finally, the paper addresses the current limitations of DDS, including in vivo stability and large-scale manufacturing, and proposes directions for overcoming these challenges through responsive polymers and advanced surface modification technologies.
KW - Drug Delivery system (DDS);Polymeric Nanoparticles;Lipid Noparticles(LNP);Stimuli-reponsive Release;Targeted Therapy;Controlled Release;Vaccine Delivery;Neurological Disocrders
DO - 10.21186/IPR.2025.10.4.179
ER -
Yun Seo Shim, Eun Ji Choi and Ja Hyun Lee. (2025). Drug Delivery Systems(DDS): Focusing on Disease Application Cases. Industry Promotion Research, 10(4), 179-189.
Yun Seo Shim, Eun Ji Choi and Ja Hyun Lee. 2025, "Drug Delivery Systems(DDS): Focusing on Disease Application Cases", Industry Promotion Research, vol.10, no.4 pp.179-189. Available from: doi:10.21186/IPR.2025.10.4.179
Yun Seo Shim, Eun Ji Choi, Ja Hyun Lee "Drug Delivery Systems(DDS): Focusing on Disease Application Cases" Industry Promotion Research 10.4 pp.179-189 (2025) : 179.
Yun Seo Shim, Eun Ji Choi, Ja Hyun Lee. Drug Delivery Systems(DDS): Focusing on Disease Application Cases. 2025; 10(4), 179-189. Available from: doi:10.21186/IPR.2025.10.4.179
Yun Seo Shim, Eun Ji Choi and Ja Hyun Lee. "Drug Delivery Systems(DDS): Focusing on Disease Application Cases" Industry Promotion Research 10, no.4 (2025) : 179-189.doi: 10.21186/IPR.2025.10.4.179
Yun Seo Shim; Eun Ji Choi; Ja Hyun Lee. Drug Delivery Systems(DDS): Focusing on Disease Application Cases. Industry Promotion Research, 10(4), 179-189. doi: 10.21186/IPR.2025.10.4.179
Yun Seo Shim; Eun Ji Choi; Ja Hyun Lee. Drug Delivery Systems(DDS): Focusing on Disease Application Cases. Industry Promotion Research. 2025; 10(4) 179-189. doi: 10.21186/IPR.2025.10.4.179
Yun Seo Shim, Eun Ji Choi, Ja Hyun Lee. Drug Delivery Systems(DDS): Focusing on Disease Application Cases. 2025; 10(4), 179-189. Available from: doi:10.21186/IPR.2025.10.4.179
Yun Seo Shim, Eun Ji Choi and Ja Hyun Lee. "Drug Delivery Systems(DDS): Focusing on Disease Application Cases" Industry Promotion Research 10, no.4 (2025) : 179-189.doi: 10.21186/IPR.2025.10.4.179
