Effect on bone environments by human nervous system (인체 신경시스템이 골 환경에 미치는 영향 )

곽한식; 이성훈; 김진희; 이준원

Effect on bone environments by human nervous system

Journal of Knowledge Information Technology and Systems
Abbr : JKITS
2011, 6(4), pp.125-132
Publisher : Korea Knowledge Information Technology Society
Research Area : Interdisciplinary Studies > Interdisciplinary Research
Published : August 31, 2011

곽한식 ¹, 이성훈 ¹, 김진희 ², 이준원 ¹

¹배재대학교
²대구한의대학교

Candidate

ABSTRACT

Acetylcholine(ACh) is all ganglionic fiber neurotransmitters in sympathetic nerve and parasympathetic nerve. And which effector cells and synepses released by parasympathetic preganglionic fiber. These the transfer of synapse is called cholinergic. Another Neurotransmiters is called norepinephrine(or noradrenaline) and in transfer of synepses is called adrenergic. Adrenergic stimulation has all the excitability and the inhibitory effect by epinephrine and norepinephrine in the blood, there are α- and β- two major receptor proteins. The two receptors for the neurotransmitter stimulated by drugs that stimulate or block is used as therapy and medical applications, these receptors has been known involved in bone metabolism by the neurotransmitters. Osteoblasts and oasteoclasts has α- and β-adrenoreceptors(β-ARs) that stimulation operate sympathetic nervous system also anabolism and catabolism of bone metabolism showned an effect. However, adrenoreceptor ligands is not known directly involved the osteoblast differentiation and function, there is need for further studies.

KEYWORDS

Acetylcholine, Adrenergic receptor, Osteoblast, Osteoclast, Adrenoreceptor, Adrenoceptor

Citation status

* References for papers published after 2023 are currently being built.

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This paper was written with support from the National Research Foundation of Korea.

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