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Development of Image Processing Program for RFLP Analysis

  • Journal of Knowledge Information Technology and Systems
  • Abbr : JKITS
  • 2011, 6(6), pp.151-156
  • Publisher : Korea Knowledge Information Technology Society
  • Research Area : Interdisciplinary Studies > Interdisciplinary Research
  • Published : December 31, 2011

Gi Weon Kim 1 정진영 2 Seok-Hun Kim 3

1초당대학교
2대전보건대학
3수원여자대학교

Candidate

ABSTRACT

RFLP analysis in molecular biology is a commonly used method. For example, RFLP analysis is used to identify mutations in the genes. RFLP method caused by genetic defects in the Mediterranean can be used to diagnose anemia. It also proved useful in diagnosing hemophilia. This method analyzes the differences in banding patterns. In general, the number of band patterns and the position of a pattern is analyzed. In this paper, we develop image processing program. The program will automatically perform RFLP analysis. First, the input DNA band patterns were pre-processed. Then the features of the input patterns were extracted. By pattern matching with the standard pattern similarity was calculated. In this paper, the number of banding patterns and location of the banding pattern was used to calculate the similarity.

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