This article aims to analyse empirically the criteria of administrative reorganization focusing on the reorganization of National Institute of Toxicological Research(NITR) in the perspective of the competing values approach. For the NITR' role, even though the increase of the hazardous materials in drugs and foods, it still remains the gap between administrative capacities. The increasing demands on the NITR are as follows. Besides toxicological research and assessment on the safety and efficacy of foods and drugs, the NITR needs to devote much effort on the biotechnology research on the safety of genetically-modified food, gene therapy, and on the development of transgenic animals, in step with the world's research and development in biotechnology. The NITR also has to contribute to the public health by assuring the safety of foods and drugs through the establishment of the nationally suitable toxicological management on the hazardous materials in foods and drugs. In conclusion, this article presents the priority of the administrative reorganization criteria. First, it analyzes the administrative environments of the NITR, and reviews organizational goals and strategies of it. Second, it reviews polity governance of the NITR. Third, it reviews organizational governance of the NITR and the related government agencies. Fourth, it looks at the benchmarking cases through comparative study. Fifth, it analyze questionnaires about the diagnoses and the development plans of the NITR from Toxicology-Professionals. Sixth, based on these analyses, it suggests the functional and organizational development plans of the NITR for the future.