Inhibitory Activity of Plant Extracts on biosynthesis of Melanin as the iological pigment on skin (피부 바이오색소인 Melanin 생합성을 억제하는 식물추출물 저해제의 탐색 )

Kim， Jin Hee (김진희); Lee, Junwon (이준원)

Inhibitory Activity of Plant Extracts on biosynthesis of Melanin as the iological pigment on skin

Journal of Knowledge Information Technology and Systems
Abbr : JKITS
2010, 5(3), pp.91-98
Publisher : Korea Knowledge Information Technology Society
Research Area : Interdisciplinary Studies > Interdisciplinary Research
Published : June 30, 2010

Kim， Jin Hee ¹, Lee, Junwon ²

¹대구한의대학교
²배재대학교

Candidate

ABSTRACT

The inhibitory effects of solvent extracts of 75 plants on melanin biosynthesis were investigated. Amongst the plant extracts, CHCl3 fraction of Juncus effusus, H2O fraction of Eupatorium chinensis, BuOH fraction of Veratrum patulum, Hexane fraction of Chionanthus retusa, and Hexane fraction of Sophora japonica showed a significant mushroom tyrosinase inhibitory effects with above 80% at 100 ㎍/㎖. Among these, BuOH fraction of Veratrum patulum will be studied further to elucidate the structure and chemical properties of the active compound responsible for melanin biosynthesis inhibitory action.

KEYWORDS

Melanin biosynthesis, mushroom tyrosinase, solvent extracts, Juncus effusus, Eupatorium chinensis

Citation status

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This paper was written with support from the National Research Foundation of Korea.

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