Journal of Knowledge Information Technology and Systems 2023 KCI Impact Factor : 0.89
-
pISSN : 1975-7700 / eISSN : 2734-0570
- https://journal.kci.go.kr/kkits
KJCKorea
Journal Central
Analysis of Anti-inflammatory Effect on Odorless Korea Propolis
- Journal of Knowledge Information Technology and Systems
- Abbr : JKITS
- 2020, 15(2), pp.275-283
- DOI : 10.34163/jkits.2020.15.2.013
- Publisher : Korea Knowledge Information Technology Society
- Research Area : Interdisciplinary Studies > Interdisciplinary Research
- Received : March 6, 2020
- Accepted : April 10, 2020
- Published : April 30, 2020
1배재대학교
Accredited
ABSTRACT
Biological properties of propolis vary with chemical composition, plant sources, geographic area and seasons. Flavonoids, which are the most important substances of propolis, have physiologically active functions such as boost immunity, antioxidant, antibacterial, anti-inflammatory, antiviral and anticancer. Propolis has been shown to be rejected by consumers due to its unique strong odor and color, so in this study, anti-inflammatory effects for NO and inflammation-related cytokines such as interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α) production were identified using propolis that effectively eliminated odors and the functionality for the effect was studied. As a result of measuring the rate of decrease of NO concentration, propolis and odorless propolis showed no decrease in concentration of 1μg/ml compared with the control, but showed significant decrease of about 74% at concentration of 10μg/ml. At a concentration of 10μg/ml of propolis, IL-1β production was reduced by about 49% and at a concentration of 10μg/ml of odorless propolis, IL-1β production was reduced by about 36% compared with the control. IL-6 production showed a decrease of about 66% and 43% at concentrations of 10μg/ml of propolis and odorless propolis, respectively, compared with the control. TNF-α production showed a decrease of about 62% and 60% at concentrations of 10μg/ml of propolis and odorless propolis, respectively, compared with the control. Based on these research results, it is expected to develop propolis material that has anti-inflammatory function and removes odors and to be used to applied to the development of health functional food technology.
Statistics
-
1,436 Viewed
-
345 Downloaded
Tools
Issue List
Citation status
* References for papers published after 2023 are currently being built.
[journal]
P. Chandna
/ 2014
/ Complementary and alternative medicine(CAM) : a review of propolis in dentistry
/ Technology
4
: 6~
[journal]
J. M. Sforcin
/ 2016
/ Biological properties and therapeutic applications of propolis
/ Phytother. Res
30
: 894~905
[journal]
V. R. Pasupuleti
/ 2017
/ Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits
/ Oxidative Med. Cell. Longevity
[journal]
J. M. Sforcin
/ 2017
/ Medical benefits of honeybee products, Evidence-Based Complement
/ Alternat. Med
[journal]
M. Lotfy
/ 2006
/ Biological activity of bee propolis in health and disease
/ Asian Pac. J. Cancer Prev
7
: 22~31
[book]
J. Fearnely
/ 2001
/ Bee propolis
/ Souvenir Press Ltd
[journal]
A. K. Kuropatnicki
/ 2013
/ Historical aspects of propolis research in modern times
/ Evidence-Based Complement. Alternat. Med
[journal]
G. C-F. Chan
/ 2013
/ The immunomodulatory and anticancer properties of propolis
/ Clin. Rev. Allergy Immunol
44
: 262~273
[other]
/ 2012
/ Propolis:Medline plus supplements
/ U.S. National Library of Medicine,
[journal]
J. M. Sforcin
/ 2011
/ Propolis : is there a potential for the development of new drugs?
/ J. Ethnopharmacol(Review)
133
: 253~260
[journal]
S. De Castro
/ 2001
/ Propolis: biological and pharmacological activities. Therapeutic uses of this bee-product
/ Ann. Rev. Biomed. Sci
3
: 49~83
[journal]
A. Ramos
/ 2007
/ Propolis : a review of its anti-inflammatory and healing actions
/ J. Venomous Anim. Toxins Incl. Trop. Dis
13
: 697~710
[journal]
K. E. Heim
/ 2002
/ Flavonoids antioxidants: chemistry, metabolism and structure activity relationship
/ J. Nutr. Biochem
13
: 572~584
[journal]
S. Kumazawa
/ 2004
/ Antioxidant activity of propolis of various geographic origins
/ Food Chemistry
84
: 329~339
[journal]
B. B. Silva
/ 2008
/ Chemical composition and botanical origin of red propolis, a new type of Brazilian propolis
/ Evidence-Based Complementary and Alternative Medicine
5
: 313~316
[journal]
V. S. Bankova
/ 2000
/ Propolis: recent advances in chemistry and plant origin
/ Apidologie
31(3)
: 15~
[journal]
C. M. Gomez
/ 2006
/ Advances in the analysis of phenolic compounds in products derived from bees
/ J. Pharm. Bio. Anal
41
: 1220~1234
[journal]
G. I. Jasprica
/ 2007
/ Evaluation of antioxidative activity of Croatian propolis samples using DPPH and ABTS stable free radical assays
/ Molecules
12
: 1006~1021
[journal]
S. M. Alencar
/ 2007
/ Chemical composition and biological activity of a new type of Brazilian propolis : red propolis
/ J. Ethnoph
113
: 278~283
[journal]
N. Kumar
/ 2008
/ Antioxidant and antimicrobial activity of propolis from Tamil Nadu zone
/ J. Med. Plants Res
2
: 361~364
[journal]
R. Christov
/ 2005
/ Chemical composition of propolis from Canada, its antiradical activity and plant origin
/ Nat. Prod. Res
19
: 673~678
[journal]
K. Bosio
/ 2000
/ In vitro activity of propolis against Streptococcus pyogenes
/ Lett. Appl. Microbiol
31
: 174~177
[journal]
G. Burdock
/ 1998
/ Review of the biological properties and toxicity of bee propolis(propolis)
/ Food. Chem. Toxicol
36
: 347~363
[journal]
V. C. Toreti
/ 2013
/ Recent progress of propolis for its biological and chemical compositions and its botanical origin, Evidence-Based Complement
/ Alternat. Med
[journal]
V. D. Wagh
/ 2013
/ Propolis: a wonder bees product and its pharmacological potentials
/ Adv. Pharmacol. Sci
[journal]
A. Parolia
/ 2010
/ Propolis and its potential uses in oral health
/ Int. J. Med. Med. Sci
2
: 210~215
[journal]
J. M. Ferreira
/ 2017
/ New propolis type from north-east Brazil: chemical composition, antioxidant activity and botanical origin
/ J. Sci. Food Agric
97
: 3552~3558
[journal]
S. Martinotti
/ 2015
/ Propolis: a new frontier for wound healing?
/ Burns Trauma
3
: 9~
[journal]
R. Omar
/ 2017
/ The chemical characterization of Nigerian propolis samples and their activity against trypanosoma bruce
/ Sci. Rep
7
: 923~
[journal]
M. Franchin
/ 2016
/ Vestitol isolated from Brazilian red propolis inhibits neutrophils migration in the inflammatory process : elucidation of the mechanism of action
/ J. Nat. Prod
79
: 954~960
[journal]
A. Parolia
/ 2010
/ Propolis and its potential uses in oral health
/ Int. J. Med. Med. Sci
2
: 210~215
[journal]
B. Machado
/ 2017
/ Propolis as an alternative in prevention and control of dental cavity
/ Immunity
19
: 24~
[journal]
M. Amoros
/ 1992
/ In vitro antiviral activity of propolis
/ Apidologie
23
: 231~240
[journal]
M. Lotfy
/ 2006
/ Biological activity of bee propolis in health and disease
/ Asian Pac. J. Cancer Prev
7
: 22~31
[journal]
F. K. A. Hady
/ 2002
/ Egyptian propolis: 2. Chemical composition, antiviral and antimicrobial activities of East Nile Delta propolis
/ Zeitschrift für Naturforschung C
57
: 386~394
[journal]
Y. M. Choi
/ 2006
/ Antioxidant and antimicrobial activities of propolis from several regions of Korea
/ LWT-Food Sci. Technol
39
: 756~761
[journal]
김성국
/ 2018
/
Anti-inflammatory Effects of Korean Propolis Extracts on Raw264.7 Macrophage Cells
/ Journal of Apiculture
/ 한국양봉학회
33(3)
: 187~194
[journal]
안영직
/ 2020
/
Analysis of Antioxidant Effect on Odorless Korea Propolis
/ 한국지식정보기술학회 논문지
/ 한국지식정보기술학회
15(1)
: 129~137
[web]
/ 2006
/ The bulletin health functional food
/ https://www.kati.net/board/pubilshedMaterialsView.do?board_seq=55205