2006, Vol.19, No.3

Anatomy & Biological Anthropology 2023 KCI Impact Factor : 0.33

pISSN : 2671-5651 / eISSN : 2671-566X
https://journal.kci.go.kr/aba

Anatomically, we have known that the first toe is composed of 2 phalangeal bones (proximal and distal phalanx) and the second, third, fourth, fifth toe are composed of 3 phalangeal bones (proximal, middle, and distal phalanx). But in Korean the 5th toe is commonly seen as 2 phalangeal bones in foot plain X-ray. In this study, we observed the numbers of phalangeal bones of fifth toe in Korean and analyzed the relation with several environmental factors and genetic factor. The data of occupation, age, body weight and foot length as well as the foot radiograph were obtained in 175 persons without any foot lesion. With the coorperative persons among them showing triphalangeal 5th toe as the index cases, radiograph of 12 family were studied to analyse the pedigree. As result, total frequency of the 5th toe symphalangism was 74.29% (male 74.2%, female 73.36%). There was no statistical difference between male and female. The bilaterality of the symphalangism was 98.46%. The occupation group were farmer, labor, self-support, white collar, student, housewife, there was no correlation between the kind of occupation and the frequency of the symphalangism. Also there was no correlation between body weight or foot length In conlusion, the two-phalanged fifth toe might be related with genetic factor rather than several environmental factors such as sex, age, occupation, body weight and length of foot. From the pedigree study we concluded the genetic trait of the triphalangism might be the autosomal recessive.

Accessory fissures serve not only as natural barriers against infection but also help in localizing any focal pulmonary parenchymal diseases and in distinguishing pleural from parenchymal diseases. Knowledge of these fissures might be useful in differentiating unusual forms of atelectasis or consolidation occuring adjacent to the fissure. Left minor fissure (LMF) is a kind of unusual accessory fissures of the left lung, which separates adjacent segments of the upper lobe as clefts of various depths lined by two layers of visceral pleura. In this study, 4 cases of LMFs found in the left upper lobe during a routine dissection of 36 cadavers were observed. Of the 4 cases, 3 cases were true LMFs which located between the anterior segment of the upper lobe and superior segment of lingula, and 1 case was considered as left azygos fissure. Among the true LMFs, 2 LMFs coursed horizontally and 1 LMF coursed upward obliquely along the costal surface. The depth of LMFs was 0.5~1.2 cm and the length was 5~8 cm.

This study was aimed to elucidate the effects of KATP activation during IPC on the PKC-ε, NF-κB and AP-1 in ischemia-reperfused rat hearts. SD male rats weighting from 300 to 350 g were split into 9 groups, such as sham control (S), IPC, 3 cycles of 5 min ischemia and 5 min reperfusion, continuous preconditioning (CP), 8 cycles of 5 min ischemia and 5 min reperfusion, KATP opening (KO) with pinacidil (1.0 mg/kg), KATP blocking with glibenclamide (1.0 mg/kg) injection, ischemia (IS), 30 min ischemia, IPC followed by IS, 8) KATP blocking and IPC followed by IS (KB+IPC+IS), IS and KATP opening (KO+IS). Heart were subjected to ligation of left descending coronary artery and reperfusion in groups of IPC, CP, IS with or without IPC. Immunohistochemistry and Western blotting for PKC-ε, NF-κB and AP-1 were performed at 3, 6, 24 hours after reperfusion or treatment. Immunoreactivities against PKC-ε antibody were observed stronger in the groups of IPC, KO, IPC+IS and KO+IS than groups of KB, IS and KB+IPC+IS. NF-κB activation and translocation were only observed in the groups of including 30 min ischemia and reperfusion. AP-1 activation and translocation were opposite to the results of PKC-ε activation. In the group of CP, KB, IS and KB+IPC+IS, reactivities of AP-1 antibody were stronger than IPC+IS, KO+IS, and weaker in the groups of S, IPC and KO. These results suggest that KATP opening with IPC or pharmacological methods may direct effect on the PKC-ε activation and that KATP blocking has effect on the AP-1 activation and translocation in the heart of ischemiareperfused of rats.