Reducing the radiation dose during CT scanning can lower the risk of radiation exposure, but not only does the image resolution significantly deteriorate, but the effectiveness of diagnosis is reduced due to the generation of noise. Therefore, noise removal from CT images is a very important and essential processing process in the image restoration. Until now, there are limitations in removing only the noise by separating the noise and the original signal in the image area. In this paper, we aim to effectively remove noise from CT images using the wavelet transform-based GAN model, that is, the WT-GAN model in the frequency domain. The GAN model used here generates images with noise removed through a U-Net structured generator and a PatchGAN structured discriminator. To evaluate the performance of the WT-GAN model proposed in this paper, experiments were conducted on CT images damaged by various noises, namely Gaussian noise, Poisson noise, and speckle noise. As a result of the performance experiment, the WT-GAN model is better than the traditional filter, that is, the BM3D filter, as well as the existing deep learning models, such as DnCNN, CDAE model, and U-Net GAN model, in qualitative and quantitative measures, that is, PSNR (Peak Signal-to-Noise Ratio) and SSIM (Structural Similarity Index Measure) showed excellent results.