The purpose of this study is to investigate the effects of the problem solving program of college students on their competencies. To this end, we developed 10 problem-solving programs as a factor of self-regulation and problem-solving, and conducted a program for 18 college students to verify their effectiveness. After the pre-post test, the mean comparison was made with SPSS 22. The result are as follows. First, the problem-solving program of university students showe d improvement of self-ability, problem-solving ability, achievement motivation, and interpersonal relationship. This appears to have changed perceptions and emotions and relationships with the activities of self-regulation, the activities of emotions, expression of emotions, and the activities of cause analysis, judgement, reasoning, problem solving, alternatives, and control, which are subcomponents of self-regulation. Second, the effect of the problem-solving program has been negative on conflict-control capabilities. This seems to be the result of heavy academic burden and part-time work stress as the semester progresses. As a result, it was found that a variety of problem-solving programs were needed to adapt to college students, and that problem-solving programs changed their perceptions, had positive effects on emotional expression, and brought about improved relationships and abilities.