The purpose of this study is to identify possible needs for system improvements and reflect them on the operation and development of the system as a result of the usability assessment of an information site in science and technology. For this study, a variety of data collection techniques, including search logs, interviews, and think-alouds, were used. The search log data was processed to quantify four evaluation aspects, which were the effectiveness, efficiency, satisfaction, and errors. The verbal data collected by think-alouds and post-interviews were used to identify possible needs of enhancement in a qualitative analysis. The comparison of the usability before and after the system enhancement revealed an increase of 15 points for effectiveness, 35 seconds decrease in efficiency, 5 points increase in satisfaction, and 1.1 errors decreased, implying an overall improvement of the usability of the current system.